Size  100ug
Cat code  200287
Species Cross-reactivity  H,R
Key Application  WB,ICC
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG1
Molecular Weight  54kDa
Sensitivity  This antibody detects endogenous levels of MPI and does not cross-react with related proteins.
Immunogen  Purified recombinant human MPI protein fragments expressed in E.coli.
UniProt Number  P34949
GeneBank ID  NM_002435.1
Subcellular location  Cytoplasm
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  Phosphohexomutase；Phosphomannose isomerase，Short name=PMI
Gene_symbol  PMI; PMI1; CDG1B
Summary  Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
UniPort summary  Function  Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Application Images :  

Western blot detection of MPI in Rat kidney,Rat brain，A549&LNCAP cell lysates and  using MPI antibody (1:1000 diluted). Predicted band size: 54KDa Observed band size: 45KDa
Immunocytochemistry stain of Hela using MPI antibody (1:300).