CD58/LFA3,淋巴细胞功能相关抗原-3抗体-抗体-抗体-生物在线
CD58/LFA3,淋巴细胞功能相关抗原-3抗体

CD58/LFA3,淋巴细胞功能相关抗原-3抗体

商家询价

产品名称: CD58/LFA3,淋巴细胞功能相关抗原-3抗体

英文名称: Anti-CD58/LFA3 antibody

产品编号: HZ-2498R

产品价格: null

产品产地: 中国/美国

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

CD58/LFA3,淋巴细胞功能相关抗原-3抗体

产品编号HZ-2498R
英文名称CD58/LFA3
中文名称淋巴细胞功能相关抗原-3抗体
别 名LFA-3; AG3; Ag3; CD58; CD58 antigen (lymphocyte function associated antigen 3)1; CD58 antigen; CD58 antigen, (lymphocyte function associated antigen 3); CD58 molecule; FLJ23181; FLJ43722; LFA 3; LFA3; LFA3_HUMAN; Lymphocyte Function Associated Antigen Type 3; Lymphocyte function-associated antigen 3; Surface glycoprotein LFA 3; Surface glycoprotein LFA-3.
说 明 书0.1ml 0.2ml
研究领域细胞生物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
CD58/LFA3,淋巴细胞功能相关抗原-3抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量25kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CD58
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CD58/LFA3,淋巴细胞功能相关抗原-3抗体PubMedPubMed
产品介绍background:
LFA3 is a type 1 transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on most hematopoietic cells and on nonhematopoietic cells such as fibroblasts, endothelial and epithelial cells. Its expression is particularly high on memory T-cells and dendritic cells. LFA3 expression on antigen-presenting cells and target cells enhances T-cells antigen recognition through binding to its ligand, LFA2/CD2, on T-cells.

Function:
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein.
Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Gene ID:
965

Database links:
Entrez Gene: 965 Human
Omim: 153420 Human
SwissProt: P19256 Human
Unigene: 34341 Human


CD58/LFA3,淋巴细胞功能相关抗原-3抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.