LILRB3/CD85a,白细胞免疫球蛋白样受体-B抗体

产品编号HZ-2691R
英文名称LILRB3/CD85a
中文名称白细胞免疫球蛋白样受体-B抗体
别 名CD85 antigen like family member A; CD85a; CD85a antigen; HL9; IL T5; ILT5; Immunoglobulin like transcript 5; Leukocyte immunoglobulin like receptor 3; Leukocyte immunoglobulin like receptor subfamily B (with TM and ITIM domains) member 3; Leukocyte immunoglobulin like receptor subfamily B member 3; LIR 3; LIR3; Gp91; Pirb; MGC138403; Monocyte inhibitory receptor HL9; PIRB; Lilrb3; 16M4; 16M5; 16M6; 6M1; 7M5; PIRB1; PIRB2; PIRB3; PIRB4;PIRB5.
说 明 书0.1ml 0.2ml
研究领域免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
LILRB3/CD85a,白细胞免疫球蛋白样受体-B抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量67kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human LILRB3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
LILRB3/CD85a,白细胞免疫球蛋白样受体-B抗体PubMedPubMed
产品介绍background:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
May act as receptor for class I MHC antigens.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Detected in monocytes and B-cells.

Gene ID:
11025

LILRB3/CD85a,白细胞免疫球蛋白样受体-B抗体Database links:
Entrez Gene: 11025 Human
Omim: 604820 Human
SwissProt: O75022 Human
Unigene: 631592 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.