别 名Neural-specific serine/arginine repetitive splicing factor of 100 kDa; Neural-specific SR-related protein of 100 kDa; nSR100; Serine/arginine repetitive matrix protein 4; Srrm4; SRRM4_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 发育生物学 神经生物学 信号转导 细胞周期蛋白 细胞分化 表观遗传学
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Sheep,
SRRM4,丝氨酸/精氨酸相关核基质蛋白4抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量69kDa
性 状Lyophilized or Liquid
免 疫 原KLH conjugated synthetic peptide derived from human SRRM4
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts.
Splicing factor specifically required for neural celldifferentiation. Acts in conjuction with nPTB/PTBP2 by bindingdirectly to its regulated target transcripts and promotesneural-specific exon inclusion in many genes that function inneural cell differentiation. Required to promote the inclusion ofneural-specific exon 10 in nPTB/PTBP2, leading to increasedexpression of neural-specific nPTB/PTBP2. Also promotes theinclusion of exon 16 in DAAM1 in neuron extracts (By similarity).
Nucleus (By similarity).
Specifically expressed in neuronal cells (atprotein level). Expressed in the cerebellum.
Phosphorylated (By similarity).
Belongs to the nSR100 family.
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.