IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体-抗体-抗体-生物在线
IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体

IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体

商家询价

产品名称: IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体

英文名称: Anti-IGSF11 antibody

产品编号: HZ-9201R

产品价格: null

产品产地: 中国/美国

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体

产品编号HZ-9201R
英文名称IGSF11
中文名称大脑和睾丸特异性免疫球蛋白超家族成员11抗体
别 名brain and testis specific immunoglobin superfamily protein; BTIGSF; CXADR like 1; CXADRL1; Igsf13; immunoglobulin superfamily member 11; Immunoglobulin superfamily member 11 precursor; MGC35227; V set and immunoglobulin domain containing 3; V set and immunoglobulin domain containing protein 3; VSIG3; IGS11_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 细胞周期蛋白 细胞膜受体 细胞表面分子 细胞分化
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量44kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human IGSF11
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体PubMedPubMed
产品介绍background:
IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Function:
Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.

Subcellular Location:
Cell Membrane, Single-pass type I membrane protein.

IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体Tissue Specificity:
bundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.

Post-translational modifications:
N-glycosylated (By similarity).

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene ID:
152404

Database links:
Entrez Gene: 152404 Human
Entrez Gene: 207683 Mouse
Entrez Gene: 303926 Rat
Omim: 608351 Human
SwissProt: Cow
SwissProt: Q5DX21 Human
SwissProt: P0C673 Mouse
SwissProt: Q5U2P2 Rat

IGSF11,大脑和睾丸特异性免疫球蛋白超家族成员11抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.