HE4,附睾分泌蛋白4抗体

产品编号HZ-4838R
英文名称HE4
中文名称附睾分泌蛋白4抗体
别 名EDDM4; epididymal protein 4; Epididymal secretory protein E4; Epididymis specific whey acidic protein type four disulfide core; HE 4; Major epididymis specific protein E4; Major epididymis-specific protein E4; Putative protease inhibitor WAP5; WAP 5; WAP domain containing protein HE4; WAP four disulfide core domain 2; WAP four disulfide core domain protein 2; WAP four-disulfide core domain protein 2; WAP5; WFDC 2; WFDC2; WFDC2_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 细胞周期蛋白 细胞类型标志物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
HE4,附睾分泌蛋白4抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量10kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Epididymal secretory protein E4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
HE4,附睾分泌蛋白4抗体PubMedPubMed
产品介绍background:
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]

Function:
Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis.

Subcellular Location:
Secreted

Tissue Specificity:
Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis.

Similarity:
Contains 2 WAP domains.

Database links:
Entrez Gene: 10406 Human
Entrez Gene: 67701 Mouse
SwissProt: Q14508 Human
SwissProt: Q9DAU7 Mouse
Unigene: 2719 Human
Unigene: 27289 Mouse

HE4,附睾分泌蛋白4抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.