Recombinant Human Interleukin-15上海信裕生物科技有限公司

性能参数

产品名称: Recombinant Human Interleukin-15
英文名称: IL-T
抗体货号: IC-101-15
产品规格: 5μg/100μg/1mg
级    别: , 分析纯, 分析纯,
产品产地: 美国
品牌商标: XY-Bioscience
价    格: 600-28500元
抗原: 详见说明书
抗原来源: 详见说明书
抗体来源: 详见说明书
适用物种: 详见说明书
详见说明书conjugate:详见说明书
Isotype:详见说明书
应用范围: > 98 % by SDS-PAGE and HPLC analyses.
更新时间: 2018/4/20 12:12:00
详细资料:  实验方法技术资料
浏览人数:39
诚信指数:1304点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
点此求购
在线QQ: 我是3002707824,请问我有什么可以帮到您呢?
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

上海信裕生物科技有限公司
地址:
上海市闵行莘庄工业区春东路508号A1-2F
邮编:
200612
电话:
021-60345312
传真:
021-37680378
联系人:
余琪
所在区域:
上海·上海
邮件:
公司展台:
在线QQ:
我是3002707824,请问我有什么可以帮到您呢?
扫一扫,关注我们

产品详细描述

 Recombinant Human Interleukin-15

Synonyms IL-T
Species
Accession P40933
GeneID 3600
Source Escherichia coli.
Molecular Weight Approximately 12.9 kDa, a single non-glycosylated polypeptide chain containing 114 amino acids.
Quantity 5µg/100µg/1mg
AA Sequence NWVNVISDLK KIEDLIQSMH IDATLYTESD VHPSCKVTAM KCFLLELQVI SLESGDASIH DTVENLIILA NNSLSSNGNV TESGCKECEE LEEKNIKEFL QSFVHIVQMF INTS
Purity > 98 % by SDS-PAGE and HPLC analyses.
Biological Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 × 106 IU/mg.
Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.
Endotoxin Less than 0.01 EU/µg of rHuIL-15 GMP as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 to -70 °C under sterile conditions after reconstitution.
Usage This GMP product can be for research use or further manufacturing use.
Quality statement The manufacture and testing of this product is in compliance with ICH Q7a guidelines.
Reference 1. Anderson DM, Johnson L, Glaccum MB, et al. 1995. Genomics, 25: 701-6.
2. Krause H, Jandrig B, Wernicke C, et al. 1996. Cytokine, 8: 667-74.
3. Chirifu M, Hayashi C, Nakamura T, et al. 2007. Nat Immunol, 8: 1001-7.
4. Grabstein KH, Eisenman J, Shanebeck K, et al. 1994. Science, 264: 965-8.
5. Giri JG, Ahdieh M, Eisenman J, et al. 1994. EMBO J, 13: 2822-30.
6. Arena A, Merendino RA, Bonina L, et al. 2000. New Microbiol, 23: 105-12.
Background Human Interleukin-15 (IL-15) is expressed by the IL15 gene located on the chromosome 4. It shares approximately 97 % and 73 % sequence identity with simian and murine IL-15, respectively. Both human and simian IL-15 are active on murine cells. IL-15 is secreted by mononuclear phagocytes (and some other cells), especially macrophages following infection by virus. It possesses a variety of biological functions, including stimulating and maintaining of cellular immune responses, especially regulating T and natural killer (NK) cell activation and proliferation. In additionally, it shares many biological properties with IL-2, including T, B and NK cell-stimulatory activities. IL-15 signals through a complex composed of IL-2/IL-15 receptor beta chain. Although IL-15 lacks sequence homology with IL-2, it has recently been shown that both the beta and gamma chains of the IL-2 receptor are utilized for IL-15 binding and signaling. In addition, an IL-15 specific binding protein has also been cloned from a mouse T cell clone

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

查看Recombinant Human Interleukin-15产品的用户还对以下产品感兴趣

暂无

ADVERTISEMENT

找不到您所需的产品,发布求购试试?

标题:*
描述:
姓名:*
Email:*
单位:*
电话:*
地址:*
邮编:
资料: 需要 不需要
报价: 需要 不需要