磷酸化N-钙粘附分子抗体上海沪震实业有限公司

性能参数

产品名称: 磷酸化N-钙粘附分子抗体
英文名称: phospho-N Cadherin (Tyr820)
抗体货号: hz-5263R
产品规格: 100ul
级    别: , , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 1580元
抗原: IgG
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 见说明书
应用范围: ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
更新时间: 2018/4/12 15:02:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-phospho-N Cadherin (Tyr820) antibody

 

产品编号 hz-5263R
英文名称 phospho-N Cadherin (Tyr820)
中文名称 ***酸化N-钙粘附分子抗体
别    名 N Cadherin (phospho Y820); p-CDH2 (Tyr820); CDH2 (phospho-Tyr820); CDH2 (phospho-T820); phospho-CDH2 (Tyr820); Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadherin neuronal; cadherin 2 type 1 N-cadherin neuronal; Cadherin2; Calcium dependent adhesion protein neuronal; CD325; CD325 antigen; CDH2; CDHN; CDw325; CDw325 antigen; N cadherin 1; NCAD; Neural Cadherin; Neural Cadherin; CADH2_HUMAN.  
   
产品类型 ***酸化抗体 
研究领域 肿瘤  免疫学  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human CDH2 around the phosphorylation site of Tyr820 [PQ(p-Y)PV]:PQ(p-Y)PV 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq, Jul 2008]. 

Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

Subcellular Location:
Cell membrane.

Similarity:
Contains 5 cadherin domains.

SWISS:
P19022

Gene ID:
1000

Database links:

Entrez Gene: 1000 Human

Entrez Gene: 12558 Mouse

Entrez Gene: 83501 Rat

Omim: 114020 Human

SwissProt: P19022 Human

SwissProt: P15116 Mouse

SwissProt: Q9Z1Y3 Rat

Unigene: 464829 Human

Unigene: 606106 Human

Unigene: 257437 Mouse

Unigene: 23200 Rat

 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

N-钙粘附分子属于依赖钙离子的细胞间糖蛋白粘附分子的一部分,主要是参与细胞间同源性粘附,调控和介导细胞间相互反应

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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