磷酸化非受体型蛋白酪氨酸磷酸酶7抗体上海沪震实业有限公司

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产品名称: 磷酸化非受体型蛋白酪氨酸磷酸酶7抗体
英文名称: phospho-PTPN7 (Ser93)
抗体货号: hz-5558R
产品规格: 100ul
级    别: , , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 1580元
抗原: IgG
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 见说明书
应用范围: WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
更新时间: 2018/8/13 13:09:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-phospho-PTPN7 (Ser93) antibody

 

产品编号 hz-5558R
英文名称 phospho-PTPN7 (Ser93)
中文名称 ***酸化非受体型蛋白酪氨酸***酸酶7抗体
别    名 PTPN7(phospho S93); BPTP 4; BPTP4; Dual specificity phosphatase 1; Hematopoietic protein tyrosine phosphatase; LC PTP; LCPTP; LPTP; Protein tyrosine phoshatase non receptor type stress induced; Protein tyrosine phoshatase nonreceptor type stress induced; Protein tyrosine phosphatase LC PTP; Protein tyrosine phosphatase non receptor type 7; PTPN 7; PTPNI; Tyrosine protein phosphatase non receptor type 7; PTN7_HUMAN.  
   
产品类型 ***酸化抗体 
研究领域 肿瘤  免疫学  信号转导  激酶和***酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human PTPN7 around the phosphorylation site of Ser93:VR(p-S)LG 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

Function:
Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.

Subunit:
Monomer. Interacts with MAPK1, MAPK3 and several other MAP kinases.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed exclusively in thymus and spleen.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. 
Contains 1 tyrosine-protein phosphatase domain.

SWISS:
P35236

Gene ID:
5778

Database links:

Entrez Gene: 5778 Human

Entrez Gene: 320139 Mouse

Entrez Gene: 246781 Rat

Omim: 176889 Human

SwissProt: P35236 Human

SwissProt: Q8BUM3 Mouse

SwissProt: P49445 Rat

Unigene: 402773 Human

Unigene: 258388 Mouse

Unigene: 10160 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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