磷酸化蛋白激酶C mu型抗体-抗体-抗体-生物在线
磷酸化蛋白激酶C mu型抗体

磷酸化蛋白激酶C mu型抗体

商家询价

产品名称: 磷酸化蛋白激酶C mu型抗体

英文名称: phospho-PRKD1 (Ser742)

产品编号: hz-5562R

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-phospho-PRKD1 (Ser742) antibody

 

产品编号 hz-5562R
英文名称 phospho-PRKD1 (Ser742)
中文名称 磷酸化蛋白激酶C mu型抗体
别    名 PKC mu (phospho S742); p-PKC mu (phospho S742); PRKD1(phospho S742); nPKC D1; nPKC mu; nPKC-D1; nPKC-mu; nPKCD1; nPKCmu; PKC; PKC MU; PKCM; PKCmu; PKD 1; PKD; PKD1; PRKCM; PRKD 1; Prkd1; Protein kinase C mu; Protein kinase C mu type; Protein kinase D; Protein kinase D1; Serine/threonine protein kinase D1; Serine/threonine-protein kinase D1; KPCD1_HUMAN.  
   
产品类型 磷酸化抗体 
研究领域 肿瘤  细胞生物  免疫学  信号转导  转录调节因子  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 102kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human PRKD1 around the phosphorylation site of Ser742:RR(p-S)VV 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM]

Function:
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.

Subcellular Location:
Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.

Similarity:
Belongs to the protein kinase superfamily. 
CAMK Ser/Thr protein kinase family. 
PKD subfamily.
Contains 1 PH domain.
Contains 2 phorbol-ester/DAG-type zinc fingers.
Contains 1 protein kinase domain.

SWISS:
Q15139

Gene ID:
5587

Database links:

Entrez Gene: 5587 Human

Entrez Gene: 18760 Mouse

Entrez Gene: 85421 Rat

Omim: 605435 Human

SwissProt: Q15139 Human

SwissProt: Q62101 Mouse

SwissProt: Q9WTQ1 Rat

Unigene: 508999 Human

Unigene: 133719 Mouse

Unigene: 144619 Rat

 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.