磷酸化蛋白酪氨酸激酶9抗体-抗体-抗体-生物在线
磷酸化蛋白酪氨酸激酶9抗体

磷酸化蛋白酪氨酸激酶9抗体

商家询价

产品名称: 磷酸化蛋白酪氨酸激酶9抗体

英文名称: phospho-PTK9 (Tyr321)

产品编号: hz-5613R

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500

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 Rabbit Anti-phospho-PTK9 (Tyr321) antibody 

 

产品编号 hz-5613R
英文名称 phospho-PTK9 (Tyr321)
中文名称 磷酸化蛋白酪氨酸激酶9抗体
别    名 PTK9 (phospho-Tyr321); PTK9 (phospho-Y321); p-PTK9 (Tyr321); p-TWF1(Y321); A6; A6 protein tyrosine kinase; Protein A6; Protein tyrosine kinase 9; PTK9; PTK9 protein tyrosine kinase 9; TWF 1; TWF1; Twinfilin 1; Twinfilin actin binding protein, homolog 1; Twinfilin; Twinfilin, actin-binding protein, homolog 1 (Drosophila); Twinfilin, Drosophila, homolog of, 1; TWF1_HUMAN; Twinfilin-1.  
   
产品类型 磷酸化抗体 
研究领域 免疫学  信号转导  结合蛋白  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human TWF1 around the phosphorylation site of Tyr321:GD(p-Y)LE 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.

Function:
Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.

Subunit:
Interacts with G-actin; ADP-actin form and capping protein (CP). May also be able to interact with TWF2 and phosphoinositides, PI(4,5)P2. When bound to PI(4,5)P2, it is down-regulated.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts.

Tissue Specificity:
Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver.

Post-translational modifications:
Phosphorylated on serine and threonine residues.

Similarity:
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. 
Contains 2 ADF-H domains.

SWISS:
Q12792

Gene ID:
5756

Database links:

Entrez Gene: 5756 Human

Entrez Gene: 506683 Cow

Entrez Gene: 19230 Mouse

Entrez Gene: 315265 Rat

Omim: 610932 Human

SwissProt: Q56JV6 Cow

SwissProt: Q12792 Human

SwissProt: Q91YR1 Mouse

SwissProt: Q5RJR2 Rat

Unigene: 5944 Cow

Unigene: 189075 Human

Unigene: 309867 Mouse

Unigene: 162971 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications