磷酸化Ras相关GTP结合蛋白抗体
产品名称： 磷酸化Ras相关GTP结合蛋白抗体
英文名称： phospho-RPH3AL(Ser232)
产品编号： hz-5695R
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
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Rabbit Anti-phospho-RPH3AL(Ser232) antibody
| 产品编号 | hz-5695R |
| 英文名称 | phospho-RPH3AL(Ser232) |
| 中文名称 | 磷酸化Ras相关GTP结合蛋白抗体 |
| 别 名 | Rph3a(phospho S232); Noc2; Rab effector Noc2; Rabphilin 3A-like (without C2 domains); Rabphilin 3A-like; Rabphilin-3A-like protein; RPH3AL; RPH3L_HUMAN; No C2 domains protein; Gm1753. |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 肿瘤 免疫学 信号转导 G蛋白偶联受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human rab effector Noc2 isoform 2 around the phosphorylation site of Ser232 [HL(p-S)GC]:HL(p-S)GC |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells. Function: Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells. Subunit: Recruited to dense-core vesicles through specific interaction with RAB27A in endocrine cells. Interacts with RAB3A, RAB3B, RAB3C and RAB3D. Interacts with ZYX. Subcellular Location: Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Recruited to the vesicle membrane in a GTP-and RAB3B-dependent manner in epithelial cells. Tissue Specificity: Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells. Similarity: Contains 1 FYVE-type zinc finger. Contains 1 RabBD (Rab-binding) domain. SWISS: Q9UNE2 Gene ID: 9501 Database links: Entrez Gene: 9501 Human Omim: 604881 Human SwissProt: Q9UNE2 Human Unigene: 651925 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |