磷酸化内收蛋白a1抗体上海沪震实业有限公司

性能参数

产品名称: 磷酸化内收蛋白a1抗体
英文名称: phospho-alpha Adducin(Ser726)
抗体货号: hz-6189R
产品规格: 100ul
级    别: , , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 1580元
抗原: IgG
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 见说明书
应用范围: ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
更新时间: 2018/4/13 16:05:00
详细资料:  实验方法技术资料
浏览人数:19
诚信指数:790点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
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电话:
021-60345367
传真:
021-31320307
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上海·中国-上海
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产品详细描述

 Rabbit Anti-phospho-alpha Adducin(Ser726) antibody

 

产品编号 hz-6189R
英文名称 phospho-alpha Adducin(Ser726)
中文名称 ***酸化内收蛋白a1抗体
别    名 alpha Adducin(phospho S726); ADD 1; ADD A; ADD1; ADD1 protein; ADDA; ADDA_HUMAN; Adducin 1 (alpha); Adducin 1 alpha; Alpha adducin; Alpha-adducin; Erythrocyte adducin alpha subunit; Erythrocyte adducin subunit alpha; MGC3339; MGC44427; OTTHUMP00000151163; OTTHUMP00000151164; OTTHUMP00000151165; OTTHUMP00000218664; OTTHUMP00000218665.   
   
产品类型 ***酸化抗体 
研究领域 免疫学  信号转导  激酶和***酸酶  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser726:651-737/737 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-Actin junction of the membrane skeleton. The cortical Actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical Actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta . Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans and spleen in mice.

Function:
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. 

Subunit:
Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit. 

Subcellular Location:
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. 

Tissue Specificity:
Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit. 

Similarity:
Belongs to the aldolase class II family. Adducin subfamily. 

Gene ID:
118

Database links:

Entrez Gene: 118 Human

Entrez Gene: 11518 Mouse

Entrez Gene: 24170 Rat

Omim: 102680 Human

SwissProt: P35611 Human

SwissProt: Q9QYC0 Mouse

SwissProt: Q63028 Rat

Unigene: 183706 Human

Unigene: 289106 Mouse

Unigene: 5788 Rat

 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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