磷酸化内收蛋白a1抗体
产品名称: 磷酸化内收蛋白a1抗体
英文名称: phospho-alpha Adducin(Ser726)
产品编号: hz-6189R
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
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Rabbit Anti-phospho-alpha Adducin(Ser726) antibody
产品编号 | hz-6189R |
英文名称 | phospho-alpha Adducin(Ser726) |
中文名称 | 磷酸化内收蛋白a1抗体 |
别 名 | alpha Adducin(phospho S726); ADD 1; ADD A; ADD1; ADD1 protein; ADDA; ADDA_HUMAN; Adducin 1 (alpha); Adducin 1 alpha; Alpha adducin; Alpha-adducin; Erythrocyte adducin alpha subunit; Erythrocyte adducin subunit alpha; MGC3339; MGC44427; OTTHUMP00000151163; OTTHUMP00000151164; OTTHUMP00000151165; OTTHUMP00000218664; OTTHUMP00000218665. |
产品类型 | 磷酸化抗体 |
研究领域 | 免疫学 信号转导 激酶和磷酸酶 细胞类型标志物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 81kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser726:651-737/737 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-Actin junction of the membrane skeleton. The cortical Actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical Actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta . Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans and spleen in mice. Function: Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. Subunit: Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit. Subcellular Location: Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Tissue Specificity: Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit. Similarity: Belongs to the aldolase class II family. Adducin subfamily. Gene ID: 118 Database links: Entrez Gene: 118 Human Entrez Gene: 11518 Mouse Entrez Gene: 24170 Rat Omim: 102680 Human SwissProt: P35611 Human SwissProt: Q9QYC0 Mouse SwissProt: Q63028 Rat Unigene: 183706 Human Unigene: 289106 Mouse Unigene: 5788 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |