磷酸化丝氨酸/苏氨酸蛋白激酶II β(casein kinase IIβ)抗体
产品名称： 磷酸化丝氨酸/苏氨酸蛋白激酶II β(casein kinase IIβ)抗体
英文名称： phospho-CK II beta (Ser209)
产品编号： hz-7909R
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
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Rabbit Anti-phospho-CK II beta (Ser209) antibody
| 产品编号 | hz-7909R |
| 英文名称 | phospho-CK II beta (Ser209) |
| 中文名称 | 磷酸化丝氨酸/苏氨酸蛋白激酶II β(casein kinase IIβ)抗体 |
| 别 名 | Casein Kinase 2 beta (phospho S209); Casein Kinase 2 beta (p-S209); p-CSK2B(Ser209); phospho-CSK2B(Ser209); Casein kinase 2 beta polypeptide; casein kinase IIβ; Casein kinase II subunit beta; CK II beta; CK2B; CK2N; CSK2B; CSK2B_HUMAN; CSNK 2B; CSNK2B; G5A; MGC138222; MGC138224; Phosvitin; Protein G5a. |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 肿瘤 细胞生物 信号转导 干细胞 细胞周期蛋白 转录调节因子 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, |
| 产品应用 | IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 24kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human CK II beta around the phosphorylation site of Ser209:FK(p-S)PV |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008]. Function: Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit. Subunit: Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. The beta subunit dimerization is mediated by zinc ions. Interacts with TCTEX1D3. Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation. Interacts with MUSK; mediates phosphorylation of MUSK by CK2. Post-translational modifications: Phosphorylated by alpha subunit. Similarity: Belongs to the casein kinase 2 subunit beta family. SWISS: P67871 Gene ID: 1460 Database links: Entrez Gene: 1460 Human Entrez Gene: 13001 Mouse Entrez Gene: 81650 Rat Omim: 115441 Human SwissProt: P67870 Human SwissProt: P67871 Mouse SwissProt: P67874 Rat Unigene: 73527 Human Unigene: 378901 Mouse Unigene: 137692 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |