Rabbit Anti-phospho-CEBPE (Thr74) antibody
|别 名||CEBPE (phospho T74); p-CEBPE (phospho T74); C/EBP epsilon; CCAAT/enhancer binding protein (C/EBP) epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein epsilon; CEBPE; CEBPE_HUMAN; CRP 1; CRP1.|
|研究领域||细胞生物 免疫学 信号转导 表观遗传学|
|交叉反应||Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,|
|产品应用||ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||31kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthesised phosphopeptide derived from human CEBPE around the phosphorylation site of Thr74.:PG(p-T)P|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.
Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.
Entrez Gene: 1053 Human
Entrez Gene: 110794 Mouse
Entrez Gene: 25410 Rat
Omim: 600749 Human
SwissProt: Q15744 Human
SwissProt: Q6PZD9 Mouse
SwissProt: P56261 Rat
Unigene: 558308 Human
Unigene: 236223 Mouse
Unigene: 44462 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications