磷酸化转录调节因子C/EBPε抗体-抗体-抗体-生物在线
磷酸化转录调节因子C/EBPε抗体

磷酸化转录调节因子C/EBPε抗体

商家询价

产品名称: 磷酸化转录调节因子C/EBPε抗体

英文名称: phospho-CEBPE (Thr74)

产品编号: hz-13823R

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500

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 Rabbit Anti-phospho-CEBPE (Thr74) antibody

 

产品编号 hz-13823R
英文名称 phospho-CEBPE (Thr74)
中文名称 磷酸化转录调节因子C/EBPε抗体
别    名 CEBPE (phospho T74); p-CEBPE (phospho T74); C/EBP epsilon; CCAAT/enhancer binding protein (C/EBP) epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein epsilon; CEBPE; CEBPE_HUMAN; CRP 1; CRP1.  
   
产品类型 磷酸化抗体 
研究领域 细胞生物  免疫学  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human CEBPE around the phosphorylation site of Thr74.:PG(p-T)P 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

Function:
C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.

Subcellular Location:
Nucleus.

Tissue Specificity:
Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.

Post-translational modifications:
Phosphorylated.

Gene ID:
1053

Database links:

Entrez Gene: 1053 Human

Entrez Gene: 110794 Mouse

Entrez Gene: 25410 Rat

Omim: 600749 Human

SwissProt: Q15744 Human

SwissProt: Q6PZD9 Mouse

SwissProt: P56261 Rat

Unigene: 558308 Human

Unigene: 236223 Mouse

Unigene: 44462 Rat

 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications