磷酸化膜突蛋白抗体-抗体-抗体-生物在线
磷酸化膜突蛋白抗体

磷酸化膜突蛋白抗体

商家询价

产品名称: 磷酸化膜突蛋白抗体

英文名称: phospho-Moesin (Thr558)

产品编号: hz-17703R

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500

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 Rabbit Anti-phospho-Moesin (Thr558) antibody

 

产品编号 hz-17703R
英文名称 phospho-Moesin (Thr558)
中文名称 磷酸化膜突蛋白抗体
别    名 Moesin (phospho T558); p-Moesin (phospho T558); Membrane organizing extension spike protein; Membrane-organizing extension spike protein; MOES_HUMAN; Moesin; Moesin/anaplastic lymphoma kinase fusion protein; MSN; MSN/ALK fusion.  
   
   
产品类型 磷酸化抗体 
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 68kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Moesin around the phosphorylation site of Thr558:YK(p-T)LR 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]

Function:
Probably involved in connections of major cytoskeletal structures to the plasma membrane.

Subcellular Location:
Cell membrane. Cytoplasm; cytoskeleton. Apical cell membrane. Cell projection; microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment.

Tissue Specificity:
In all tissues and cultured cells studied.

Post-translational modifications:
Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures.

Similarity:
Contains 1 FERM domain.

Gene ID:
4478

Database links:

Entrez Gene: 4478 Human

Entrez Gene: 17698 Mouse

Omim: 309845 Human

SwissProt: P26038 Human

SwissProt: P26041 Mouse

Unigene: 87752 Human

Unigene: 138876 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications