磷酸化巨噬细胞集落刺激因子受体抗体上海沪震实业有限公司

性能参数

产品名称: 磷酸化巨噬细胞集落刺激因子受体抗体
英文名称: phospho-MCSF Receptor (Tyr561)
抗体货号: hz-18735R
产品规格: 100ul
级    别: , , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 1580元
抗原: IgG
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 见说明书
应用范围: WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
更新时间: 2018/4/17 15:35:00
详细资料:  实验方法技术资料
浏览人数:10
诚信指数:730点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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上海·中国-上海
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产品详细描述

 Rabbit Anti-phospho-MCSF Receptor (Tyr561) antibody 

 

产品编号 hz-18735R
英文名称 phospho-MCSF Receptor (Tyr561)
中文名称 ***酸化巨噬细胞集落刺激因子受体抗体
别    名 MCSF Receptor (phospho Y561); p-MCSF Receptor (phospho Y561); C FMS; CD 115; CD115; CD115 antigen; CFMS; Colony stimulating factor 1 receptor; Colony stimulating factor I receptor; CSF 1 R; CSF 1R; CSF-1 receptor; CSF-1-R; CSF1 R; CSF1R; CSF1R_HUMAN; CSFR; FIM 2; FIM2; FMS; FMS proto oncogene; FMS protooncogene; HDLS; M-CSF Receptor; M-CSF-R; Macrophage colony stimulating factor 1 receptor; Macrophage colony stimulating factor I receptor; Macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v fms) oncogene homolog; Oncogen FMS; Proto-oncogene c-Fms; V-FMS McDonough feline sarcoma viral oncogen homolog, formerly.  
   
产品类型 ***酸化抗体 
研究领域 细胞生物  免疫学  信号转导  激酶和***酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 120kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human phospho-MCSF Receptor (Tyr561):NS(p-Y)TF 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

Function:
Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed in bone marrow and in differentiated blood mononuclear cells.

Similarity:
Belongs to the protein kinase superfamily. 
Tyr protein kinase family. 
CSF-1/PDGF receptor subfamily. 
Contains 5 Ig-like C2-type (immunoglobulin-like) domains. 
Contains 1 protein kinase domain.

Gene ID:
1436

Database links:

Entrez Gene: 1436 Human

Entrez Gene: 12978 Mouse

Omim: 164770 Human

SwissProt: P07333 Human

SwissProt: P09581 Mouse

Unigene: 586219 Human

Unigene: 22574 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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