磷酸化胸苷激酶1抗体上海沪震实业有限公司

性能参数

产品名称: 磷酸化胸苷激酶1抗体
英文名称: phospho-Thymidine Kinase 1 (Ser13)
抗体货号: hz-19666R
产品规格: 100ul
级    别: , , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 1580元
抗原: IgG
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 见说明书
应用范围: WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (
更新时间: 2018/4/18 13:59:00
详细资料:  实验方法技术资料
浏览人数:22
诚信指数:832点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
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邮编:
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上海·中国-上海
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产品详细描述

 Rabbit Anti-phospho-Thymidine Kinase 1 (Ser13) antibod

 

产品编号 hz-19666R
英文名称 phospho-Thymidine Kinase 1 (Ser13)
中文名称 ***酸化胸苷激酶1抗体
别    名 Thymidine Kinase 1 (phospho S13); p-Thymidine Kinase 1 (phospho S13); cytosolic; KITH_HUMAN; Thymidine kinase 1; Thymidine kinase 1 soluble; Thymidine kinase 1 soluble isoform; Thymidine kinase; Thymidine kinase cytosolic; TK 1; TK 2; TK1; Tk1a; Tk1b; TK2.  
   
   
产品类型 ***酸化抗体 
研究领域 细胞生物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Dog, Pig, Hamster, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Thymidine Kinase 1 around the phosphorylation site of Ser13:PG(pS)PS 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. Because of this, Thymidine Kinase can be used as a proliferation marker in the diagnosis, treatment, and follow-up of malignant diseases, especially hematological malignancies. Thymidine Kinase may be observed as a monomer, dimer, trimer or tetramer.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Phosphorylated on Ser-13 in mitosis.

Similarity:
Belongs to the thymidine kinase family.

Gene ID:
7083

Database links:

Entrez Gene: 7083 Human

Entrez Gene: 21877 Mouse

Entrez Gene: 24834 Rat

Omim: 188300 Human

SwissProt: P04183 Human

SwissProt: P04184 Mouse

SwissProt: P27158 Rat

Unigene: 515122 Human

Unigene: 2661 Mouse

Unigene: 195325 Rat

Unigene: 216486 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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