Rabbit Anti-TRIM29 (acetyl K116) antibody
|英文名称||TRIM29 (acetyl K116)|
|别 名||Ataxia telangiectasia group D associated protein; Ataxia telangiectasia group D-associated protein; ATDC; FLJ36085; TRI29_HUMAN; TRIM 29; TRIM29; Tripartite motif containing 29; Tripartite motif containing protein 29; Tripartite motif protein 29; Tripartite motif protein TRIM29; Tripartite motif-containing protein 29.|
|研究领域||细胞生物 免疫学 信号转导 转录调节因子 表观遗传学|
|交叉反应||Human, Pig, Cow, Rabbit,|
|产品应用||WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||66kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated Synthesised acetylpeptide derived from human TRIM29 around the acetylation site of K116:AK(Ac-K)PP|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.
Cytoplasm. Colocalizes with intermediate filaments.
Expressed in placenta, prostate and thymus.
Constitutively phosphorylated by PKC on serine/threonine in A431 cells.
Contains 1 B box-type zinc finger.
Entrez Gene: 23650 Human
Entrez Gene: 525062 Cow
Entrez Gene: 72169 Mouse
Entrez Gene: 300656 Rat
Omim: 610658 Human
SwissProt: Q14134 Human
SwissProt: Q8R2Q0 Mouse
Unigene: 504115 Human
Unigene: 273277 Mouse
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.