河豚毒素单克隆抗体-抗体-抗体-生物在线
河豚毒素单克隆抗体

河豚毒素单克隆抗体

商家询价

产品名称: 河豚毒素单克隆抗体

英文名称: TTX(5E7)

产品编号: hz-0919M

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ELISA=1:500-1000

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
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  • 所在区域 : 上海
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 Mouse Anti-TTX(5E7) antibody

 

产品编号 hz-0919M
英文名称 TTX(5E7)
中文名称 河豚毒素单克隆抗体
别    名 TETRODOTOXIN; Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d] pyrimidine-4,7,10,11,12-pentol  
   
产品类型 药物与化合物抗体 
研究领域 免疫学  药物及化合物  海洋生物  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 5E7
交叉反应 TTX
产品应用 ELISA=1:500-1000 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 0.31927kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated to TTX: 
亚    型 IgG
纯化方法 affinity purified by Protein G
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Tetrodotoxin, frequently abbreviated as TTX, is a potent neurotoxin with no known antidote. There have been successful tests of a possible antidote in mice, but further tests must be carried out to determine efficacy in humans. Fampridine has been shown to reverse tetrodotoxin toxicity in animal experiments.
Tetrodotoxin blocks action potentials in nerves by binding to the voltage-gated, fast sodium channels in nerve cell membranes, essentially preventing any affected nerve cells from firing by blocking the channels used in the process. The binding site of this toxin is located at the pore opening of the voltage-gated Na+ channel. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish or mola, and triggerfish, several species that carry the toxin. Although tetrodotoxin was discovered in these fish and found in several other animals (e.g., blue-ringed octopus, rough-skinned newt, and Naticidae) it is actually produced by certain symbiotic bacteria, such as Pseudoalteromonas tetraodonis, certain species of Pseudomonas and Vibrio, as well as some others that reside within these animals.

SWISS:
N/A

CAS:
4368-28-9

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications