FITC标记的味觉受体蛋白家族2亚基7抗体
产品名称： FITC标记的味觉受体蛋白家族2亚基7抗体
英文名称： Anti-TAS2R7/FITC
产品编号： HZ-11615R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-TAS2R7/FITC Conjugated antibody
FITC标记的味觉受体蛋白家族2亚基7抗体
| 产品编号 | bs-11615R-FITC |
| 英文名称 | Anti-TAS2R7/FITC |
| 中文名称 | FITC标记的味觉受体蛋白家族2亚基7抗体 |
| 别 名 | STC7 4; T2R30; T2R6; T2R7; TA2R7_HUMAN; Tas2r130; Tas2r6; TAS2R7; Taste receptor family B member 4; Taste receptor type 2 member 7; TRB4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 信号转导 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 37kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TAS2R7/T2R7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The sense of taste provides animals with valuable information about the quality and nutritional value of food. A family of G protein-coupled receptors are involved in taste perception and include T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Single taste receptor cells express a variety of T2Rs, suggesting that each cell is capable of recognizing multiple tastants. T2R6 (also designatedT2R30, mt2r42, STC 7-4 or taste receptor, type 2, member 130) is an integral membrane receptor protein in mice that may play a role in the perception of bitterness and in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate Alpha-gustducin, mediate PLC-Beta-2 activation and lead to the gating of TRPM5. T2R6 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. The human homolog of T2R6, designated T2R7 (TAS2R7, TRB4 or taste receptor, type 2, member 7) is a G protein-coupled receptor expressed in taste receptor cells of the tongue and palate epithelia. Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Similarity: Belongs to the G-protein coupled receptor T2R family. Database links: Entrez Gene: 50837 Human Entrez Gene: 387355 Mouse Entrez Gene: 690334 Rat SwissProt: Q9NYW3 Human SwissProt: P59530 Mouse SwissProt: Q9JKE9 Rat Unigene: 533754 Human Unigene: 377916 Mouse Unigene: 134167 Rat Omim: 604793 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
味觉为动物提供了有关食物质量和营养价值的有价值的信息。G蛋白偶联受体家族参与味觉感知，包括T1R，参与甜味和鲜味感知，T2R参与苦味感知。这两种类型的味觉受体耦合到各种G蛋白，以启动信号转导级联。单一味觉受体细胞表达多种T2RS，提示每个细胞能够识别多种味道物质。T2R6（也被指定为T2R30，MT2R42，STC 7- 4或味觉受体，2型，成员130）在小鼠中是一种完整的膜受体蛋白，其在感知苦味和感测胃肠内容物的化学成分中起作用。该受体的活性可刺激α-促胃泌素，介导PLC-BETA-2活化，并导致TrPM5的门控。T2R6在舌和腭上皮味觉感受器细胞亚群中表达，且仅在胃泌素阳性细胞中表达。T2R6的人类同源物（T2R7，TRB4或味觉受体，2型，成员7）是舌和腭上皮的味觉感受器细胞中表达的G蛋白偶联受体。