FITC标记的味觉受体蛋白家族2亚基9抗体
产品名称： FITC标记的味觉受体蛋白家族2亚基9抗体
英文名称： Anti-TAS2R9/FITC
产品编号： HZ-11613R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-TAS2R9/FITC Conjugated antibody
FITC标记的味觉受体蛋白家族2亚基9抗体
| 产品编号 | bs-11613R-FITC |
| 英文名称 | Anti-TAS2R9/FITC |
| 中文名称 | FITC标记的味觉受体蛋白家族2亚基9抗体 |
| 别 名 | T2R9; Taste receptor, family B, member 6; Taste receptor, type 2, member 9; TRB6; TA2R9_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TAS2R9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: TAS2R9 belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. TAS2R9 is implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. It signals through PLCB2 and the calcium regulated cation channel TRPM5. Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity). Subcellular Location: Membrane; Multipass membrane protein. Tissue Specificity: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Similarity: Belongs to the G-protein coupled receptor T2R family. Database links: Entrez Gene: 50835 Human Omim: 604795 Human SwissProt: Q9NYW1 Human Unigene: 272391 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
TAS2R9属于G-蛋白偶联受体超家族成员的候选味觉受体家族。这些蛋白在舌和腭上皮的味觉感受器细胞中特异性表达。它们在基因组中排列成群，并与影响小鼠和人类痛苦感知的基因座联系在一起。在功能性表达研究中，它们对苦味物质有反应。该基因定位于12p13染色体上的味觉受体基因簇。TAS2R9与口腔和胃肠道中苦味化合物的感知有关。它通过PLCB2和钙调节的阳离子通道Trp5信号。