Rabbit Anti-GNAT2/FITC Conjugated antibody
|别 名||ACHM4; Cone type transducin alpha subunit; GNAT 2; GNAT C; Gnat2; GNAT2_HUMAN; GNATC; Guanine nucleotide binding protein (G protein) alpha transducing; polypeptide 2; Guanine nucleotide binding protein G t subunit alpha 2; Guanine nucleotide-binding protein G(t) subunit alpha-2; Transducin alpha 2; Transducin alpha-2 chain; Transducin alpha2; Transducin cone specific alpha polypeptide.|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||神经生物学 信号转导 G蛋白信号|
|交叉反应||Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||40kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human GNAT2 (2-100aa)|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Retinal rod outer segment.
Defects in GNAT2 are the cause of achromatopsia type 4 (ACHM4) [MIM:139340]. Achromatopsia is an autosomal recessively inherited visual disorder that is present from birth and that features the absence of color discrimination.
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Entrez Gene: 2780 Human
Entrez Gene: 14686 Mouse
Entrez Gene: 365901 Rat
Omim: 139340 Human
SwissProt: P19087 Human
SwissProt: P50149 Mouse
Unigene: 36973 Human
Unigene: 439652 Mouse
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications