FITC标记的G蛋白转录因子α2/Gα t2抗体
产品名称: FITC标记的G蛋白转录因子α2/Gα t2抗体
英文名称: Anti-GNAT2/FITC
产品编号: HZ-11560R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GNAT2/FITC Conjugated antibody
FITC标记的G蛋白转录因子α2/Gα t2抗体
产品编号 | bs-11560R-FITC |
英文名称 | Anti-GNAT2/FITC |
中文名称 | FITC标记的G蛋白转录因子α2/Gα t2抗体 |
别 名 | ACHM4; Cone type transducin alpha subunit; GNAT 2; GNAT C; Gnat2; GNAT2_HUMAN; GNATC; Guanine nucleotide binding protein (G protein) alpha transducing; polypeptide 2; Guanine nucleotide binding protein G t subunit alpha 2; Guanine nucleotide-binding protein G(t) subunit alpha-2; Transducin alpha 2; Transducin alpha-2 chain; Transducin alpha2; Transducin cone specific alpha polypeptide. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 神经生物学 信号转导 G蛋白信号 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 40kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GNAT2 (2-100aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase. Subunit: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Tissue Specificity: Retinal rod outer segment. DISEASE: Defects in GNAT2 are the cause of achromatopsia type 4 (ACHM4) [MIM:139340]. Achromatopsia is an autosomal recessively inherited visual disorder that is present from birth and that features the absence of color discrimination. Similarity: Belongs to the G-alpha family. G(i/o/t/z) subfamily. Database links: Entrez Gene: 2780 Human Entrez Gene: 14686 Mouse Entrez Gene: 365901 Rat Omim: 139340 Human SwissProt: P19087 Human SwissProt: P50149 Mouse Unigene: 36973 Human Unigene: 439652 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
转导蛋白是一种3亚基鸟嘌呤核苷酸结合蛋白(G蛋白),它刺激视神经过程中视紫红质和cGMP磷酸二酯酶的偶联。杆和锥体中的转导子α亚基由单独的基因编码。该基因编码锥体中的α亚基。