FITC标记的膜转运蛋白DISPA抗体上海沪震实业有限公司

性能参数

产品名称: FITC标记的膜转运蛋白DISPA抗体
英文名称: Anti-Dispatched/FITC
抗体货号: HZ-11549R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/6/13 16:29:00
详细资料:  实验方法技术资料
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诚信指数:754点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
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电话:
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联系人:
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上海·中国-上海
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产品详细描述

 Rabbit Anti-Dispatched/FITC Conjugated antibody

FITC标记的膜转运蛋白DISPA抗体

 

产品编号 bs-11549R-FITC
英文名称 Anti-Dispatched/FITC
中文名称 FITC标记的膜转运蛋白DISPA抗体
别    名 DISP1; DISP 1; disp1; DISP1_HUMAN; DISPA; Dispatched A; Dispatched homolog 1; DKFZP434I0428; FLJ43740; MGC104180; MGC13130; MGC16796; Protein dispatched homolog 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 信号转导  转运蛋白  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 171kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Dispatched (301-400aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]

Function:
Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal

Subcellular Location:
Membrane; Multi-pass membrane protein 

Similarity:
Belongs to the dispatched family.
Contains 1 SSD (sterol-sensing) domain.

Database links:

Entrez Gene: 84976 Human

Entrez Gene: 68897 Mouse

Omim: 607502 Human

SwissProt: Q96F81 Human

SwissProt: Q3TDN0 Mouse

Unigene: 528817 Human

Unigene: 358721 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

导致胚胎结构正常发育的细胞增殖和分化的模式通常取决于分泌蛋白信号的局部产生。特定信号源周围的细胞根据信号的有效浓度以分级方式响应,并且该响应产生构成成熟结构的细胞类型的模式。在Drosophila已经鉴定出一种新的片段极性基因,其蛋白产物是正常的刺猬信号(HD)所必需的。该基因是果蝇的两个人类同源物之一,并且基于其与小鼠相对应的序列同源性,编码的蛋白可能在早期胚胎中的HH图案化活动中起着至关重要的作用。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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