FITC标记的神经肽W抗体上海沪震实业有限公司

性能参数

产品名称: FITC标记的神经肽W抗体
英文名称: Anti-NPW/Neuropeptide W/FITC
抗体货号: HZ-11531R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/6/14 8:36:00
详细资料:  实验方法技术资料
浏览人数:7
诚信指数:754点
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使用范围:仅限科研使用,不能应用于临床
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供应商联系卡

上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-NPW/Neuropeptide W/FITC Conjugated antibody

FITC标记的神经肽W抗体

 

产品编号 bs-11531R-FITC
英文名称 Anti-NPW/Neuropeptide W/FITC
中文名称 FITC标记的神经肽W抗体
别    名 hPPL8; L8; L8C; Neuropeptide W; PPL8; PPNPW; Preproprotein L8; NPW_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 3kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuropeptide W (33-55aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
NPW is a 165 amino acid secreted protein that is cleaved into two chains: neuropeptide W-23 (also designated NPW23 or L8) and neuropeptide W-30 (also known as NPW30 or L8C). Both NPW neuropeptides activate G-protein coupled receptors in the central nervous system to enhance cortisol secretion. Highly expressed in lymphoblastic leukemia, colorectal adenocarcinoma, fetal kidney, trachea and substantia nigra, NPW is also found at low levels in placenta, ovary, testis and uterus. NPW functions in organization of neuroendocrine signals and is also thought to enhance food and water intake as well as stress responses. The gene encoding NPW maps to human chromosome 16p13.3.

Function:
NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. 

Subcellular Location:
Secreted

Tissue Specificity:
Detected at high levels in the substantia nigra, fetal kidney and trachea; at lower levels in testis, uterus, ovary and placenta. Not detectable in many regions of the central nervous system. Also detected at high levels in lymphoblastic leukemia and colorectal adenocarcinoma. 

Similarity:
Belongs to the neuropeptide B/W family. 

Database links:
Entrez Gene: 283869 Human
Omim: 607997 Human
SwissProt: Q8N729 Human


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

NPW是一种165氨基酸分泌蛋白,被裂解成两条链:神经肽W-23(也被命名为NPW23或L8)和神经肽W-30(也称为NPW30或L8C)。两个NPW神经肽激活中枢神经系统中的G蛋白偶联受体以增强皮质醇分泌。在淋巴母细胞白血病、结直肠腺癌、胎儿肾脏、气管和黑质中高表达,NPW在胎盘、卵巢、睾丸和子宫中也低水平。NPW在神经内分泌信号的组织中起作用,并被认为可以增强食物和水分的摄入以及应激反应。编码NPW的基因定位于人类染色体16p133。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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