FITC标记的甘丙肽受体3抗体上海沪震实业有限公司

性能参数

产品名称: FITC标记的甘丙肽受体3抗体
英文名称: Anti-GALR3/FITC
抗体货号: HZ-11528R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/6/14 8:39:00
详细资料:  实验方法技术资料
浏览人数:7
诚信指数:754点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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供应商联系卡

上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
所在区域:
上海·中国-上海
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公司展台:
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产品详细描述

 Rabbit Anti-GALR3/FITC Conjugated antibody

 

FITC标记的甘丙肽受体3抗体

 

产品编号 bs-11528R-FITC
英文名称 Anti-GALR3/FITC
中文名称 FITC标记的甘丙肽受体3抗体
别    名 GAL 3R; GAL R3; GAL3 R; GAL3-R; GAL3R; Galanin receptor 3; Galanin receptor-3; Galanin receptor family member 3; Galanin receptor type 3; GALN R3; GALNR 3; GALNR3; GALR 3; GALR-3; Galr3; GALR3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  信号转导  通道蛋白  细胞膜受体  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Horse, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GALR3 (1-100aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.

Function:
Receptor for the hormone galanin.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:
UniProtKB/Swiss-Prot: O60755.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

人和大鼠GALR3 A 368和370氨基酸蛋白分别属于G蛋白偶联受体家族,其结合神经肽Galin,分布于中枢和外周神经系统、垂体、胃肠道和内分泌。胰腺外分泌和外分泌。GALR3 mRNA广泛分布,但表达量低。在人中,GalR3 mRNA在下丘脑、垂体和睾丸中高表达,在肾上腺和胰腺中表达较少。大鼠和人GALR3与钾通道亚基GYK1和GYK4共同表达。与GALR1一样,GalR3信号通路导致腺苷酸环化酶的抑制和钾通道的激活,这与调节神经递质释放有关。甘丙肽与甘丙肽受体的结合导致进食增加、学习受损、阿片镇痛增强和阿片位置偏爱减少。

 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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