FITC标记的神经肽Y受体5抗体
产品名称： FITC标记的神经肽Y受体5抗体
英文名称： Anti-NPY5R/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围：
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-NPY5R/FITC Conjugated antibody
FITC标记的神经肽Y受体5抗体
| 产品编号 | bs-11521R-FITC |
| 英文名称 | Anti-NPY5R/FITC |
| 中文名称 | FITC标记的神经肽Y受体5抗体 |
| 别 名 | Neuropeptide Y receptor type 5; Neuropeptide Y receptor Y5; NPY 5R; NPY R5; NPY Y5; NPY Y5 receptor; NPY-Y5 receptor; NPY5 R; NPY5-R; NPY5R; NPY5R_HUMAN; NPYR 5; NPYR5; NPYY 5; NPYY5; NPYY5-R; Y5 receptor. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Dog, Cow, Horse, Rabbit, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NPY5R (1-100aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31. Function: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Brain; hypothalamus. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 4889 Human Entrez Gene: 18168 Mouse Entrez Gene: 25340 Rat Omim: 602001 Human SwissProt: Q15761 Human SwissProt: O70342 Mouse SwissProt: Q63634 Rat Unigene: 519058 Human Unigene: 598503 Human Unigene: 10685 Mouse Unigene: 10532 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
胰腺多肽（PP）、神经肽Y（NPY）和肽YY（PYY）与36种氨基酸有关。已经分离出许多与这些肽相关的结构受体，NPY1-R、NPY2-R、NPY3-R、NPY4-R、NPY5-R和NPY-6 R NPY4-R在包括脑、冠状动脉和回肠在内的多个人类组织中表达。NPY4-R映射到人类染色体10q11.2。从大鼠下丘脑分离的NPY-5R编码456个氨基酸蛋白，其总体身份与已知的Y型受体不到35%。人NPY5-R序列几乎与人NPY1-R序列相反，但与人NPY1-R序列相反。NPY5-R定位于下丘脑室旁核、外侧下丘脑以及与控制摄食行为的作用一致的其他部位。编码NPY5-R的基因定位于人类染色体4q32.2。NPY6R在人的心脏和骨骼肌中大量表达，编码NPY6R的基因定位于人类染色体5q31。