FITC标记的神经肽Y受体5抗体上海沪震实业有限公司

性能参数

产品名称: FITC标记的神经肽Y受体5抗体
英文名称: Anti-NPY5R/FITC
抗体货号: HZ-
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: 
更新时间: 2018/6/14 8:48:00
详细资料:  实验方法技术资料
浏览人数:9
诚信指数:754点
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使用范围:仅限科研使用,不能应用于临床
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供应商联系卡

上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-NPY5R/FITC Conjugated antibody

FITC标记的神经肽Y受体5抗体

 

产品编号 bs-11521R-FITC
英文名称 Anti-NPY5R/FITC
中文名称 FITC标记的神经肽Y受体5抗体
别    名 Neuropeptide Y receptor type 5; Neuropeptide Y receptor Y5; NPY 5R; NPY R5; NPY Y5; NPY Y5 receptor; NPY-Y5 receptor; NPY5 R; NPY5-R; NPY5R; NPY5R_HUMAN; NPYR 5; NPYR5; NPYY 5; NPYY5; NPYY5-R; Y5 receptor.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  通道蛋白  细胞膜受体  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Dog, Cow, Horse, Rabbit, 
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NPY5R (1-100aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31.

Function:
Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Brain; hypothalamus.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:
Entrez Gene: 4889 Human
Entrez Gene: 18168 Mouse
Entrez Gene: 25340 Rat
Omim: 602001 Human
SwissProt: Q15761 Human
SwissProt: O70342 Mouse
SwissProt: Q63634 Rat
Unigene: 519058 Human
Unigene: 598503 Human
Unigene: 10685 Mouse
Unigene: 10532 Rat


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

胰腺多肽(PP)、神经肽Y(NPY)和肽YY(PYY)与36种氨基酸有关。已经分离出许多与这些肽相关的结构受体,NPY1-R、NPY2-R、NPY3-R、NPY4-R、NPY5-R和NPY-6 R NPY4-R在包括脑、冠状动脉和回肠在内的多个人类组织中表达。NPY4-R映射到人类染色体10q11.2。从大鼠下丘脑分离的NPY-5R编码456个氨基酸蛋白,其总体身份与已知的Y型受体不到35%。人NPY5-R序列几乎与人NPY1-R序列相反,但与人NPY1-R序列相反。NPY5-R定位于下丘脑室旁核、外侧下丘脑以及与控制摄食行为的作用一致的其他部位。编码NPY5-R的基因定位于人类染色体4q32.2。NPY6R在人的心脏和骨骼肌中大量表达,编码NPY6R的基因定位于人类染色体5q31。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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