FITC标记的CD39样蛋白1抗体
产品名称： FITC标记的CD39样蛋白1抗体
英文名称： Anti-ENTPD2/FITC
产品编号： HZ-11515R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-ENTPD2/FITC Conjugated antibody
FITC标记的CD39样蛋白1抗体
| 产品编号 | bs-11515R-FITC |
| 英文名称 | Anti-ENTPD2/FITC |
| 中文名称 | FITC标记的CD39样蛋白1抗体 |
| 别 名 | CD39 antigen like 1; CD39 antigen-like 1; CD39 like1; CD39L1; CD39like1; ecto ATP diphosphohydrolase 2; ecto ATPase 2; ecto ATPDase 2; Ecto-ATP diphosphohydrolase 2; Ecto-ATPase 2; Ecto-ATPDase 2; ectoATPase 2; ectoATPDase 2; Ectonucleoside triphosphate diphosphohydrolase 2; ENTP2_HUMAN; Entpd2; NTPDase 2; NTPDase2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ENTPD2/CD39L1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events. Function: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Brain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes. Similarity: Belongs to the GDA1/CD39 NTPase family. Database links: Entrez Gene: 954 Human Entrez Gene: 12496 Mouse Entrez Gene: 64467 Rat Omim: 602012 Human SwissProt: Q9Y5L3 Human SwissProt: O55026 Mouse SwissProt: O35795 Rat Unigene: 123036 Human Unigene: 482100 Mouse Unigene: 8276 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
CD39，也称为核苷三磷酸二磷酸水解酶1（Enp1），是作为细胞外核苷酸水解酶的整体膜糖蛋白。CD39通过水解ADP至AMP并最终产生腺苷抑制ADP诱导的血小板聚集。细胞内CD39在6个N-糖基化位点发生糖基化，并转移到膜上，以作为活性酶。CD39 L1是一种495氨基酸多通道膜蛋白，需要钙和镁辅因子水解ATP和其他核苷酸来调节生精神经传递。CD39 L1在肾、结肠、心脏、睾丸、胰腺、脑、前列腺、骨骼肌、小肠和卵巢中均有表达。作为替代剪接事件的结果，产生了两种CD39 L1异构体。