FITC标记的精子鞭毛蛋白2抗体
产品名称： FITC标记的精子鞭毛蛋白2抗体
英文名称： Anti-Sperm Flagellar 2/FITC
产品编号： HZ-11488R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-Sperm Flagellar 2/FITC Conjugated antibody
FITC标记的精子鞭毛蛋白2抗体
| 产品编号 | bs-11488R-FITC |
| 英文名称 | Anti-Sperm Flagellar 2/FITC |
| 中文名称 | FITC标记的精子鞭毛蛋白2抗体 |
| 别 名 | KPL2; MGC102842; Protein KPL2; SPEF2; sperm flagellar protein 2; FLJ23164; FLJ23577; FLJ25395; KIAA1770; SPEF2_HUMAN; CT122. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KPL2/Sperm Flagellar 2 (227-275aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Flagella and cillia are both membrane-bound projections from the cell surface that beat in distinctive patterns. Cilia are shorter and usually more profuse than flagella and contain a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane. The ciliary membranes of all cilia hold specific receptors and ion channel proteins that initiate signaling pathways that regulate motility and/or link mechanical or chemical stimuli to intracellular transduction cascades regulating differentiation, migration and cell growth during development and in adulthood. KPL2, also known as SPEF2 (sperm flagellar 2), is a 1,822 amino acid protein that contains a calponin homology domain, three nuclear localization signals, a consensus P-loop and a proline-rich region. Required for correct axoneme develoment, KPL2 is predominantly expressed in cells with cilia or flagella. Four isoforms of KPL2 exists as a result of alternative splicing events. Function: Required for correct axoneme develoment Similarity: Contains 1 CH (calponin-homology) domain. Database links: Entrez Gene: 79925 Human SwissProt: Q9C093 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Flagella和CyLa都是细胞表面的膜结合投射物，它们以独特的模式跳动。纤毛较短，通常比鞭毛更丰富，含有微管细胞骨架，纤毛轴索，被睫状膜包围。所有纤毛的睫状膜含有特异性受体和离子通道蛋白，它们启动信号转导通路，调节运动和/或连接机械或化学刺激，使细胞在发育过程中调节分化、迁移和细胞生长的细胞内转导级联。成年时。KPL2，也称为SPEF2（精子鞭毛2），是一种含有1822个氨基酸的蛋白质，包含一个调冷素同源结构域，三个核定位信号，一个一致的p-环和一个富含脯氨酸的区域。正确的轴突发育所需的KPL2主要在纤毛或鞭毛的细胞中表达。作为替代剪接事件的结果存在KPL2的四种异构体。