FITC标记的跨膜蛋白SEMA4F抗体
产品名称： FITC标记的跨膜蛋白SEMA4F抗体
英文名称： Anti-SEMA4F/FITC
产品编号： HZ-11478R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-SEMA4F/FITC Conjugated antibody
FITC标记的跨膜蛋白SEMA4F抗体
| 产品编号 | bs-11478R-FITC |
| 英文名称 | Anti-SEMA4F/FITC |
| 中文名称 | FITC标记的跨膜蛋白SEMA4F抗体 |
| 别 名 | M SEMA; m Sema M; PRO2353; Sema domain immunoglobulin domain (Ig) transmembrane; Sema M; Sema W; SEMAM; Semaphorin M; Semaphorin W; SEMAW; SEM4F_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 细胞分化 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 80kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SEMA4F (239-288aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4F (semaphorin-4F), also known as SEMAM, SEMAW or PRO2353, is a 770 amino acid member of the semaphorin family. Localized to the membrane, SEMA4F is a single-pass type I protein that is involved in growth cone collapse of retinal ganglion-cell axons. SEMA4F is highly expressed in postnatal brain and lung and contains one immunogloblin-like (Ig-like) domain, one PSI domain and one semaphorin domain. Two isoforms exist due to alternative splicing events. Function: SEMA4F has growth cone collapse activity against retinal ganglion-cell axons. Subcellular Location: Membrane; Single-pass type I membrane protein Similarity: Belongs to the semaphorin family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 PSI domain. Contains 1 Sema domain. Database links: UniProtKB/Swiss-Prot: O95754.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SimaPrrin是从昆虫到人类保守的细胞表面和分泌蛋白家族。这一家族蛋白质的成员长度约为750个氨基酸（包括信号序列），并由包含14-16个半胱氨酸的大约500个氨基酸的保守的胞外“信号素”域所定义，保守序列的区块和没有明显的重复。分泌和细胞结合的信号量化学吸引和排斥神经轴突的生长，引导复杂的神经组织网络的发展。Sima4F（SimaPrac-4F），也称为SAMAM，SeMW或PRO3553，是SimaPrRin家族的770氨基酸成员。SIMA4F是一种单程通过的I型蛋白，参与视网膜神经节细胞轴突的生长锥塌陷。SEMA4F在出生后的脑和肺中高表达，并含有一个免疫球蛋白样结构域，一个PSI结构域和一个信号素域。两种异构体由于选择性剪接事件而存在。