FITC标记的蛙皮降压肽抗体
产品名称: FITC标记的蛙皮降压肽抗体
英文名称: Anti-Sauvagine/FITC
产品编号: HZ-
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Sauvagine/FITC Conjugated antibody
FITC标记的蛙皮降压肽抗体
产品编号 | bs-11424R-FITC |
英文名称 | Anti-Sauvagine/FITC |
中文名称 | FITC标记的蛙皮降压肽抗体 |
别 名 | Sauvagin; Sauvagine; SVG; SAUV_PHYSA. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | frog |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 4.6kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from frog Sauvagine (C-QGPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Sauvagine is a 40-residue peptide isolated and characterized from frog skin. It shares significant structural homology with and elicits similar biological responses as corticotropin-releasing factor (CRF). It has high affinity for both the CRF1 and CRF2 receptors (and low affinity for the CRF binding protein), suggesting its potential as a pharmacological tool for the study of these receptor sub-types. Due to the binding to CRF2 receptors and their role in the release of ACTH and beta-endorphin during stress, possible areas of research with this ligand include anxiety, depression and obesity. Function: Hypotensive and diuretic peptide. Subcellular Location: Secreted. Similarity: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. Database links: UniProtKB/Swiss-Prot: P01144.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Survivin是从蛙皮中分离和鉴定的40个残基肽。它与促肾上腺皮质释放因子(CRF)具有显著的结构同源性,并引起相似的生物学反应。它对CRF1和CRF2受体(以及CRF结合蛋白的低亲和力)具有高亲和性,表明其作为研究这些受体亚型的药理学工具的潜力。由于与CRF2受体的结合及其在ACTH和β-内啡肽释放过程中的作用,这种配体可能的研究领域包括焦虑、抑郁和肥胖。