FITC标记的G蛋白偶联受体FM4/神经调节肽U受体2抗体上海沪震实业有限公司

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产品名称: FITC标记的G蛋白偶联受体FM4/神经调节肽U受体2抗体
英文名称: Anti-NMUR2/FITC
抗体货号: HZ-11421R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/8 12:28:00
详细资料:  实验方法技术资料
浏览人数:14
诚信指数:1026点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-NMUR2/FITC Conjugated antibody

FITC标记的G蛋白偶联受体FM4/神经调节肽U受体2抗体

 

产品编号 bs-11421R-FITC
英文名称 Anti-NMUR2/FITC
中文名称 FITC标记的G蛋白偶联受体FM4/神经调节肽U受体2抗体
别    名 FM4; G protein coupled receptor FM 4; G protein coupled receptor TGR 1; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; Neuromedin U receptor 2; Neuromedin-U receptor 2; NMU R2; NMU-R2; NMU2R; NMUR2; NMUR2_HUMAN; TGR1; GPR-FM4  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  神经生物学  细胞膜受体  G蛋白偶联受体  G蛋白信号  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NMUR2 (181-230aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It’s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues. 

Function:
Receptor for the neuromedin-U and neuromedin-S neuropeptides.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 56923 Human

Omim: 605108 Human

SwissProt: Q9GZQ4 Human

Unigene: 283093 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

神经调节素U是一种在平滑肌上具有高活性的神经肽。它在胃肠系统和中枢神经系统(CNS)中广泛表达。神经激肽U的外周活动包括平滑肌刺激、肠内离子转运改变和局部血流量和肾上腺皮质功能的调节。神经介素U受体1和2(NMUR1和NMUR2)是属于G-蛋白偶联受体1家族蛋白的多程膜蛋白。NMUR1和NMur2都是神经肽U神经肽的受体。NMUR1在外周器官中检测,尤其在泌尿生殖系统和胃肠系统中,睾丸中最高水平。其在中枢神经系统中的表达较低,但在小脑、海马、背根神经节和脊髓中均有检测。NMur2主要在中枢神经系统中检测,在延髓、脊髓和丘脑中检测到最高水平。它也可以在睾丸中检测到,但在外周组织中的表达水平较低。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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