FITC标记的G蛋白偶联受体66/神经调节肽U受体1抗体
产品名称： FITC标记的G蛋白偶联受体66/神经调节肽U受体1抗体
英文名称： Anti-NMUR1/FITC
产品编号： HZ-11420R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围：
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-NMUR1/FITC Conjugated antibody
FITC标记的G蛋白偶联受体66/神经调节肽U受体1抗体
| 产品编号 | bs-11420R-FITC |
| 英文名称 | Anti-NMUR1/FITC |
| 中文名称 | FITC标记的G蛋白偶联受体66/神经调节肽U受体1抗体 |
| 别 名 | FM-3; G protein-coupled receptor 66; G-protein coupled receptor 66; G-protein coupled receptor FM-3; GPR66; Growth hormone secretagogue receptor family Member 3; Neuromedin U Receptor 1; Neuromedin-U receptor 1; NMU-R1; NMUR1; NMUR1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NMUR1 (31-80aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It’s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues. Function: Receptor for the neuromedin-U and neuromedin-S neuropeptides. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 10316 Human Omim: 604153 Human SwissProt: Q9HB89 Human Unigene: 471619 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
神经调节素U是一种在平滑肌上具有高活性的神经肽。它在胃肠系统和中枢神经系统（CNS）中广泛表达。神经激肽U的外周活动包括平滑肌刺激、肠内离子转运改变和局部血流量和肾上腺皮质功能的调节。神经介素U受体1和2（NMUR1和NMUR2）是属于G-蛋白偶联受体1家族蛋白的多程膜蛋白。NMUR1和NMur2都是神经肽U神经肽的受体。NMUR1在外周器官中检测，尤其在泌尿生殖系统和胃肠系统中，睾丸中最高水平。其在中枢神经系统中的表达较低，但在小脑、海马、背根神经节和脊髓中均有检测。NMur2主要在中枢神经系统中检测，在延髓、脊髓和丘脑中检测到最高水平。它也可以在睾丸中检测到，但在外周组织中的表达水平较低。