FITC标记的脑型肉碱棕榈酰转移酶1C抗体上海沪震实业有限公司

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产品名称: FITC标记的脑型肉碱棕榈酰转移酶1C抗体
英文名称: Anti-Cpt1c/FITC
抗体货号: HZ-11416R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/8/13 13:01:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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邮编:
200612
电话:
021-60345367
传真:
021-31320307
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陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-Cpt1c/FITC Conjugated antibody

FITC标记的脑型肉碱棕榈酰转移酶1C抗体

 

产品编号 bs-11416R-FITC
英文名称 Anti-Cpt1c/FITC
中文名称 FITC标记的脑型肉碱棕榈酰转移酶1C抗体
别    名 CPT1-C; Carnitine acyltransferase like protein 1; Carnitine acyltransferase like protein1; Carnitine O palmitoyltransferase I, brain isoform; Carnitine palmitoyltransferase 1, brain; Carnitine palmitoyltransferase 1C; Carnitine palmitoyltransferase I related C; Carnitine palmitoyltransferase1C; CAT L1; CATL 1; CATL1; CPT 1 like pseudogene; Cpt 1c; CPT 1P; CPT I C; Cpt1 c; CPT1 like pseudogene; CPT1P ; CPTIC.CPT1C_HUMAN  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  细胞生物  神经生物学  信号转导  内分泌病  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
细胞定位 细胞膜 线粒体
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cpt1c (121-170aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine. 

Subcellular Location:
Mitochondrion outer membrane; Multi-pass membrane protein 

Tissue Specificity:
Expressed predominantly in brain and testis.

Similarity:
Belongs to the carnitine/choline acetyltransferase family.

Database links:
UniProtKB/Swiss-Prot: Q8TCG5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

蛋白质的CTP1家族是线粒体线粒体膜蛋白,通过线粒体调节脂肪酸的进入和氧化。Malonyl CoA,脂肪酸合成中的一个中间体,被认为是能量敏感系统的调节成分,它能进入下丘脑神经元以赋予能量稳态。下丘脑中丙二酰辅酶A水平受禁食和摄食的动态调节,改变随后的摄食行为。CTP1C,脑特异性肉碱O-棕榈酰基转移酶1,被认为是传达有关丙二酰辅酶A水平的信息,下丘脑神经元表达食欲原和厌食神经肽,调节食物摄入量和外周能量消耗。与其他CTP1蛋白不同,CTP1C结合丙二酰辅酶A,但不催化丙二酰基从CoA转移到肉碱。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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