FITC标记的睾丸特异激酶底物蛋白抗体上海沪震实业有限公司

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产品名称: FITC标记的睾丸特异激酶底物蛋白抗体
英文名称: Anti-TSKS/FITC
抗体货号: HZ-11413R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/14 12:23:00
详细资料:  实验方法技术资料
浏览人数:7
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
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上海·中国-上海
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产品详细描述

 Rabbit Anti-TSKS/FITC Conjugated antibody

FITC标记的睾丸特异激酶底物蛋白抗体

 

产品编号 bs-11413R-FITC
英文名称 Anti-TSKS/FITC
中文名称 FITC标记的睾丸特异激酶底物蛋白抗体
别    名 STK22 substrate 1; Stk22s1; Testis specific kinase substrate; Testis specific serine kinase substrate; TSKS; TSKS1; MGC134104; TSKS_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  发育生物学  神经生物学  信号转导  干细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TSKS (121-170aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
TSKS is a 592 amino acid protein that is highly expressed in human testicular tissue. Low levels of TSKS are detectable in prostate, placenta, fetal liver, thymus, and mammary gland tissues. TSKS is found to be downregulated in cancerous testicular tissue from seminoma, teratocarcinoma, embryonal and Leydig cell tumors concurrently with high expression in neighboring premalignant carcinoma. TSKS protein contains an N-terminal signal peptide, but does not contain a transmembrane region. TSKS has many potential phosphorylation and glycosylation sites and is phosphorylated by soluble recombinant TSSK2 in vitro. It is thought that TSKS likely plays a physiological role in spermatogenesis or spermiogenesis.

Function:
A novel putative serine/threonine kinase substrate gene (TSKS, for testis-specific kinase substrate) is likely the human homolog of the mouse testis-specific serine kinase substrate gene. TSKS exhibits high levels of expression exclusively in human testicular tissue. The expression of TSKS is downregulated in cancerous testicular tissue, in comparison to adjacent normal tissue. These observations suggest a role of TSKS in testicular physiology, most probably in the process of spermatogenesis or spermiogenesis. 

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Highly expressed in testis. Expressed at low levels in prostate, female breast, placenta, ovary and thymus. 

Post-translational modifications:
Phosphorylated on serine residue(s) by STK22A/TSSK1 and STK22B/TSSK2. 

Database links:

Entrez Gene: 60385 Human

Omim: 608253 Human

SwissProt: Q9UJT2 Human

Unigene: 515858 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

TSKS是一种在人睾丸组织中高表达的592氨基酸蛋白。低水平的TSKs在前列腺、胎盘、胎肝、胸腺和乳腺组织中可检测到。TSKs在睾丸精原细胞瘤、畸胎瘤、胚胎和睾丸间质细胞瘤等癌组织中的表达下调,同时在癌旁组织中高表达。TSKs蛋白含有N-末端信号肽,但不包含跨膜区。TSKs具有许多潜在的***酸化和糖基化位点,并被可溶性重组TSK2***酸化。认为TSK在精子发生或精子发生过程中可能起生理作用。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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