FITC标记的G蛋白偶联受体135/松弛素受体3抗体上海沪震实业有限公司

性能参数

产品名称: FITC标记的G蛋白偶联受体135/松弛素受体3抗体
英文名称: Anti-Relaxin 3 receptor 1/FITC
抗体货号: HZ-11405R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/7/15 11:17:00
详细资料:  实验方法技术资料
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诚信指数:824点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-Relaxin 3 receptor 1/FITC Conjugated antibody

FITC标记的G蛋白偶联受体135/松弛素受体3抗体

 

产品编号 bs-11405R-FITC
英文名称 Anti-Relaxin 3 receptor 1/FITC
中文名称 FITC标记的G蛋白偶联受体135/松弛素受体3抗体
别    名 Relaxin Receptor 3; G protein coupled receptor GPCR135; G protein coupled receptor SALPR; G-protein coupled receptor SALPR; GPCR SALPR; GPCR 135; GPCR135; Gprotein coupled receptor SALPR; Relaxin 3 receptor 1; Relaxin 3 receptor1; Relaxin 3/INSL7 receptor 1; Relaxin 3/INSL7 receptor1; Relaxin family peptide receptor 3; Relaxin family peptide receptor3; Relaxin/insulin like family peptide receptor 3; Relaxin3 receptor 1; Relaxin3 receptor1; RL3 R1; RL3R 1; RL3R1; RLN3 receptor 1; RLN3 receptor1; RLN3R1; RXFPR3; SALP R; SALPR; somatostatin and angiotensin like peptide receptor; RL3R1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Relaxin Receptor 3 (11-58aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Relaxin Receptor 3 is a G protein-coupled receptor that binds Relaxin 3 and influences differentiation and maintenance of the nervous system. Relaxin Receptor 3 shares sequence similarity with somatostatin receptors and angiotensin receptors. It mediates central processing of sensory signals in the rat and is thought to be a modulator of stress responses. Relaxin Receptor 3 is present in the brain, with highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, and low level expression in cerebellum. In peripheral tissues there are high levels in adrenal glands and low levels in pancreas, salivery gland, placenta, mammary gland and testis.

Function:
GPCR SALPR, also known as Relaxin 3 Receptor 1 (RXFP3), is a G-protein coupled receptor that is one of the physiological targets for relaxin 3, an insulin-like hormone. Activation of GPCR SALPR results in phosphorylation of ERK1/2. GPCR SALPR has been implicated in anxiety and obesity. A role for relaxin 3 and GPCR SALPR in reproductive function through the hypothalamic-pituitary-gonadal (HPG) axis has also been described. 

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 51289 Human

Entrez Gene: 239336 Mouse

Entrez Gene: 294807 Rat

Omim: 609445 Human

SwissProt: Q9NSD7 Human

SwissProt: Q8BGE9 Mouse

Unigene: 170146 Human

Unigene: 209312 Mouse

Unigene: 127658 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

松弛素受体3是一种G蛋白偶联受体,结合松弛素3并影响神经系统的分化和维持。松弛素受体3与生长抑素受体和血管紧张素受体具有序列相似性。它介导大鼠感觉信号的中枢处理,被认为是应激反应的调节剂。松弛素受体3存在于脑中,在黑质和垂体中表达最高,其次是海马、脊髓、杏仁核、尾状核和胼胝体,小脑中表达水平低。在外周组织中,肾上腺、唾液腺、胎盘、乳腺和睾丸中的肾上腺和低水平高水平。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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