FITC标记的20号染色体开放阅读框100抗体
产品名称: FITC标记的20号染色体开放阅读框100抗体
英文名称: Anti-GCX1/C20orf100/FITC
产品编号: HZ-11402R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-GCX1/C20orf100/FITC Conjugated antibody
FITC标记的20号染色体开放阅读框100抗体
产品编号 | bs-11402R-FITC |
英文名称 | Anti-GCX1/C20orf100/FITC |
中文名称 | FITC标记的20号染色体开放阅读框100抗体 |
别 名 | Chromosome 20 open reading frame 100; Chromosome 20 open reading frame 100; dJ1108D11.2; dJ495O3.1; GCX 1; GCX1; GCX-1; Granulosa cell HMG box protein 1; MGC15880; Weakly similar to NONHISTONE CHROMOSOMAL PROTEIN 6A [S.cerevisiae]; Weakly similar to NONHISTONE CHROMOSOMAL PROTEIN 6A [S.cerevisiae]; TOX2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 神经生物学 信号转导 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 52kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GCX1/C20orf100 (225-270aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: GCX-1 is a 488 amino acid transcription activator that is restricted to expression in the hypothalamus, pituitary, ovary, testis and uterus. Human reproduction is controlled by the hypothalamic-pituitary gonadal axis (HPGA) that is laid down early in fetal development. This expression pattern in the HPGA suggests that this nuclear protein is likely related to specific events in reproduction, particularly in the female. GCX-1 contains a HMG-box domain, which is commonly found in proteins that function as intercellular regulators and transcriptional co-regulators, and are found to be involved in important events such as sex determination and in the regulation of T cell differentiation. There are two isoforms of GCX-1 which are produced as a result of alternative splicing events. Function: C20orf100 is a putative transcriptional activator involved in the hypothalamo-pituitary-gonadal system. It may regulate follicular development and other processes related to female reproduction. Subcellular Location: Nuclear Similarity: Contains 1 HMG box DNA-binding domain. Database links: Entrez Gene: 84969 Human Entrez Gene: 269389 Mouse Entrez Gene: 311615 Rat Omim: 611163 Human SwissProt: Q96NM4 Human SwissProt: Q76IQ7 Rat Unigene: 26608 Human Unigene: 129021 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GCX-1是一个488个氨基酸转录激活子,仅限于下丘脑、垂体、卵巢、睾丸和子宫的表达。人类生殖是由下丘脑-垂体-性腺轴(HPGA)控制的,它在胎儿发育早期就已存在。在HPGA中的这种表达模式表明,这种核蛋白可能与生殖中的特定事件有关,特别是在女性中。GCX-1包含一个HMG盒结构域,通常在作为细胞间调节器和转录共调节器的蛋白质中发现,并且被发现参与重要的事件,如性别决定和T细胞分化的调节。GCX-1的两种异构体是作为选择性剪接事件的结果而产生的。