FITC标记的早期未分化视网膜及晶状体蛋白EURL抗体
产品名称： FITC标记的早期未分化视网膜及晶状体蛋白EURL抗体
英文名称： Anti-TSPEAR/FITC
产品编号： HZ-9577R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-TSPEAR/FITC Conjugated antibody
FITC标记的早期未分化视网膜及晶状体蛋白EURL抗体
| 产品编号 | bs-9577R-FITC |
| 英文名称 | Anti-TSPEAR/FITC |
| 中文名称 | FITC标记的早期未分化视网膜及晶状体蛋白EURL抗体 |
| 别 名 | C21orf14; C21orf38; C21orf7; Chromosome 21 open reading frame 38; Chromosome 21 open reading frame 91; Early undifferentiated retina and lens; EURL; Protein EURL homolog; YG81; TSEAR_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 72kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TSPEAR/C21orf9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis. Function: C21orf91 belongs to the EURL family. There are three named isoforms. The exact function of C21orf91 remains unknown. Subcellular Location: Secreted. Similarity: Contains 7 EAR repeats. Contains 1 laminin G-like domain. Database links: Entrez Gene: 54149 Human Entrez Gene: 67102 Mouse Entrez Gene: 360692 Rat SwissProt: Q9NYK6 Human SwissProt: Q9D7G4 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
TSPEAR，也称为C21Orf9，是一种669氨基酸分泌蛋白。TSPEAR表达的两种异构体由选择性剪接产生，包含一个血小板反应素N端结构域和七耳（癫痫相关重复）结构域。耳部结构存在于多种蛋白质中，包括TSPEAR，编码于与癫痫发作相关的染色体区域内的基因。据认为，耳域在癫痫的发病机制中发挥作用，要么结合未知的癫痫配体或干扰轴突突触发生。