FITC标记的酸敏感钾离子通道蛋白3抗体上海沪震实业有限公司

性能参数

产品名称: FITC标记的酸敏感钾离子通道蛋白3抗体
英文名称: Anti-KCNK3/FITC
抗体货号: HZ-
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/7/12 10:53:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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上海·中国-上海
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产品详细描述

 Rabbit Anti-KCNK3/FITC Conjugated antibody

FITC标记的酸敏感钾离子通道蛋白3抗体

 

英文名称 Anti-KCNK3/FITC
中文名称 FITC标记的酸敏感钾离子通道蛋白3抗体
别    名 cTBAK 1; Acid sensitive potassium channel protein TASK 1; Cardiac two pore background K(+) channel; K2p3.1; OAT1; potassium channel, subfamily K, member 3; rTASK; TASK 1; TBAK1; TWIK related acid sensitive K+ channel; Two pore potassium channel KT3.1; KCNK3; TASK; TASK1; PPH4; TASK; TASK-1; TBAK1; KCNK3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  通道蛋白  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNK3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008].

Function:
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:
Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.

Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Database links:

Entrez Gene: 3777 Human

Entrez Gene: 16527 Mouse

Entrez Gene: 29553 Rat

Omim: 603220 Human

SwissProt: O14649 Human

SwissProt: Q53SU2 Human

SwissProt: O35111 Mouse

SwissProt: O54912 Rat

Unigene: 645288 Human

Unigene: 439936 Mouse

Unigene: 15536 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

该基因编码钾通道蛋白的超家族成员,其包含两个孔形成的P结构域。编码的蛋白质是对细胞外pH变化敏感的向外整流通道,并且受到胞外酸化的抑制。也被称为酸敏感钾通道,它被麻醉剂氟烷和激活。虽然在Northern印迹中检测到三个转录本,但目前没有序列可用于确认该基因的转录变体。[由RefSeq,Aug 2008提供]。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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