FITC标记的同源盒蛋白HOXA9抗体
产品名称: FITC标记的同源盒蛋白HOXA9抗体
英文名称: Anti-HOXA9/FITC
产品编号: HZ-6667R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
上海沪震实业有限公司
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- 邮编 : 200612
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Rabbit Anti-HOXA9/FITC Conjugated antibody
FITC标记的同源盒蛋白HOXA9抗体
英文名称 | Anti-HOXA9/FITC |
中文名称 | FITC标记的同源盒蛋白HOXA9抗体 |
别 名 | ABD-B; Abd-B, drosophila, homolog of; D6a9; Homeobox protein A9; Homeobox 1G; Homeobox A9; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; Homeobox protein Hox-A9; Hox-1.7; Hox-1.7, mouse, homolog of; HOX1; Hox1.7; Hox1G; Hox1r5; Hoxa-9; Hoxa7; HOXA9/MSI2 fusion gene, included; HOXA9/NUP98 fusion gene, included; HXA9_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 发育生物学 干细胞 转录调节因子 内皮细胞 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 26, 30kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HOXA9 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: HOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells. HOXA9 expression changes dramatically with age - a uniformly low level of expression during early adulthood is replaced by a frequently very high expression in adults over sixty. Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Subcellular Location: Nucleus. Similarity: Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 396096 Chicken Entrez Gene: 100725915 Guinea pig Entrez Gene: 3205 Human Entrez Gene: 15405 Mouse Entrez Gene: 500126 Rat Omim: 142956 Human SwissProt: Q98924 Chicken SwissProt: P51783 Guinea pig SwissProt: P31269 Human SwissProt: P09631 Mouse Unigene: 659350 Human Unigene: 4694 Mouse Unigene: 203714 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
HOXA9是一种转录因子,在造血和白血病中具有中心作用。造血细胞中高水平的HOXA9表达是急性髓性白血病(AML)的一个特征,并且可能足以导致这种疾病。HOXA 9的过度表达显著地促进造血干细胞的扩增。HOXA9的表达随着年龄的增长而显著变化,在成年早期的表达水平很低,在六十岁以上的成年人中经常被很高的表达所取代。