FITC标记的G蛋白偶联受体24抗体
产品名称: FITC标记的G蛋白偶联受体24抗体
英文名称: Anti-GPR24/FITC
产品编号: HZ-6626R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-GPR24/FITC Conjugated antibody
FITC标记的G蛋白偶联受体24抗体 |
英文名称 | Anti-GPR24/FITC |
中文名称 | FITC标记的G蛋白偶联受体24抗体 |
别 名 | MCHR; G protein coupled receptor 24; GPCR MCH1; GPCR SLC/MCH1; GPR24; MCH receptor 1; MCH1R; Melanin concentrating hormone receptor 1; SLC-1; Somatostatin receptor like protein; MCHR1_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 神经生物学 G蛋白偶联受体 G蛋白信号 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 46kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MCHR/GPR24 (81-125aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: MCHR, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR does not seem to bind somatostatin. Function: Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. Subunit: Interacts with NCDN. Subcellular Location: Cell Membrane; multi-pass membrane protein Tissue Specificity: Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 2847 Human Entrez Gene: 207911 Mouse Entrez Gene: 83567 Rat Omim: 601751 Human SwissProt: Q99705 Human SwissProt: Q8JZL2 Mouse SwissProt: P97639 Rat Unigene: 248122 Human Unigene: 323523 Mouse Unigene: 10822 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
MGR是G蛋白偶联受体家族1的成员,是一种结合黑色素浓缩的完整质膜蛋白。MCHR能抑制cAMP的积累,刺激细胞内钙离子的流动,可能参与食物消耗的神经元调控。虽然结构类似生长抑素受体,MCHR似乎不结合生长抑素。