FITC标记的棕榈酰蛋白硫酯酶1抗体-抗体-抗体-生物在线
FITC标记的棕榈酰蛋白硫酯酶1抗体

FITC标记的棕榈酰蛋白硫酯酶1抗体

商家询价

产品名称: FITC标记的棕榈酰蛋白硫酯酶1抗体

英文名称: Anti-PPT1/FITC

产品编号: HZ-6619R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

Rabbit Anti-PPT1/FITC Conjugated antibody

FITC标记的棕榈酰蛋白硫酯酶1抗体

 

英文名称 Anti-PPT1/FITC
中文名称 FITC标记的棕榈酰蛋白硫酯酶1抗体
别    名 CLN1; INCL; Palmitoyl protein hydrolase 1; Palmitoyl protein thioesterase 1; Palmitoyl-protein hydrolase 1; Palmitoyl-protein thioesterase 1; PPT; PPT-1; PPT1; PPT1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PPT1 (201-250aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.

Function:
Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.

Subcellular Location:
Lysosome.

DISEASE:
Defects in PPT1 are the cause of neuronal ceroid lipofuscinosis type 1 (CLN1) [MIM:256730]. A form of neuronal ceroid lipofuscinosis with variable age at onset. Infantile, late-infantile, juvenile, and adult onset have been reported. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material, and clinically by seizures, dementia, visual loss, and/or cerebral atrophy. The lipopigment pattern seen most often in CLN1 is referred to as granular osmiophilic deposits (GROD). 

Similarity:
Belongs to the palmitoyl-protein thioesterase family.

Database links:

Entrez Gene: 281421 Cow

Entrez Gene: 5538 Human

Entrez Gene: 19063 Mouse

Entrez Gene: 29411 Rat

Omim: 600722 Human

SwissProt: P45478 Cow

SwissProt: P50897 Human

SwissProt: O88531 Mouse

SwissProt: P45479 Rat

Unigene: 3873 Human

Unigene: 277719 Mouse

Unigene: 1574 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

在溶酶体降解过程中,从蛋白质或肽中从修饰的半胱氨酸残基中除去硫酯连接的脂肪酰基,如棕榈酸盐。优选14至18个碳原子的酰基链长度。