FITC标记的γ氨基丁酸运载蛋白1抗体
产品名称: FITC标记的γ氨基丁酸运载蛋白1抗体
英文名称: Anti-GAT1/GABA Transporter 1/FITC
产品编号: HZ-6617R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-GAT1/GABA Transporter 1/FITC Conjugated antibody
FITC标记的γ氨基丁酸运载蛋白1抗体
英文名称 | Anti-GAT1/GABA Transporter 1/FITC |
中文名称 | FITC标记的γ氨基丁酸运载蛋白1抗体 |
别 名 | GABATHG; GABATR; GABT 1; GABT1; GAT-1; SLC6A1; Sodium and chloride dependent GABA transporter 1; Solute carrier family 6 (neurotransmitter transporter GABA) member 1; Solute carrier family 6 member 1. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 神经生物学 转运蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Guinea Pig, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 66kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GABA Transporter 1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: GABA Transporter 1/GAT1 is a gamma-amino butyric acid (GABA) transporter. After its release from interneurons in the CNS, the major inhibitory neurotransmitter GABA is taken up by GABA transporters (GATs). The predominant neuronal GABA transporter GAT1 is localized in GABAergic axons and nerve terminals, where it is thought to influence GABAergic synaptic transmission by removing GABA from the synaptic cleft. Function: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Subunit: Interacts with MPP5. Subcellular Location: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons. Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily. Database links: Entrez Gene: 415960 Chicken Entrez Gene: 6529 Human Entrez Gene: 232333 Mouse Entrez Gene: 79212 Rat Omim: 137165 Human SwissProt: P30531 Human SwissProt: P31648 Mouse SwissProt: P23978 Rat Unigene: 443874 Human Unigene: 5260 Mouse Unigene: 10035 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GABA转运体1/GAT1是γ-氨基丁酸(GABA)转运体。在中枢神经系统的中间神经元释放后,inhibitory neurotransmitter GABA转运蛋白(GATs)占据了主要的GABA。主要的神经元GABA转运体GAT1定位于GABA能轴突和神经末梢,在那里被认为通过从突触裂中去除GABA而影响GABA能突触传递。