FITC标记的胞浆支链氨基酸酸转氨酶抗体上海沪震实业有限公司

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产品名称: FITC标记的胞浆支链氨基酸酸转氨酶抗体
英文名称: Anti-BCAT1/FITC
抗体货号: HZ-6613R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/8/2 13:57:00
详细资料:  实验方法技术资料
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诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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供应商联系卡

上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-BCAT1/FITC Conjugated antibody

FITC标记的胞浆支链氨基酸酸转氨酶抗体

 

英文名称 Anti-BCAT1/FITC
中文名称 FITC标记的胞浆支链氨基酸酸转氨酶抗体
别    名 cytosolic; BCAT; BCAT(c); Bcat1; BCAT1_HUMAN; BCT1; Branched chain amino acid aminotransferase, cytosolic; Branched-chain-amino-acid aminotransferase; ECA39; MECA39; PNAS 121; Protein ECA39.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BCAT1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010].

Function:
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.

Subunit:
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.

Similarity:
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Database links:

Entrez Gene: 586 Human

Entrez Gene: 12035 Mouse

Omim: 113520 Human

SwissProt: P54687 Human

SwissProt: P24288 Mouse

Unigene: 438993 Human

Unigene: 4606 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

该基因编码酶支链氨基酸转氨酶的胞质形式。该酶催化支链α-***酸的可逆转氨基转移到细胞生长所必需的支链L-氨基酸。两种不同的临床疾病已被归因于支链氨基酸转氨酸的缺陷:高缬氨酸血症和高亮氨酸异亮氨酸血症。由于还存在编码这种酶的线粒体形式的基因,这两种基因中的突变可能导致这些疾病。另外,已经描述了剪接转录变体。[ RefSeq,2010年5月提供]。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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