FITC标记的骨形态发生蛋白15抗体-抗体-抗体-生物在线
FITC标记的骨形态发生蛋白15抗体

FITC标记的骨形态发生蛋白15抗体

商家询价

产品名称: FITC标记的骨形态发生蛋白15抗体

英文名称: Anti-BMP15/FITC

产品编号: HZ-6612R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围:

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-BMP15/FITC Conjugated antibody 

FITC标记的骨形态发生蛋白15抗体

 

英文名称 Anti-BMP15/FITC
中文名称 FITC标记的骨形态发生蛋白15抗体
别    名 BMP 15; BMP-15; BMP15; BMP15_HUMAN; Bone morphogenetic protein 15; GDF 9B; GDF-9B; GDF9B; Growth/differentiation factor 9B; ODG2; POF4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  发育生物学  染色质和核信号  信号转导  干细胞  生长因子和激素  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BMP15
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The BMP15 protein is a member of the bone morphogenetic protein family which is part of the transforming growth factor beta superfamily. The transforming growth factor beta superfamily includes large families of growth and differentiation factors. It is thought that BMP15 may be involved in oocyte maturation and follicular development as a homodimer, or by forming heterodimers with a related protein, Gdf9.

Function:
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.

Subunit:
Homodimer. But, in contrast to other members of this family, cannot be disulfide-linked.

Subcellular Location:
Secreted.

DISEASE:
Defects in BMP15 are the cause of ovarian dysgenesis type 2 (ODG2) [MIM:300510]; also known as X-linked hypergonadotropic ovarian dysgenesis or hypergonadotropic ovarian failure due to ovarian dysgenesis. Ovarian dysgenesis leads to ovarian failure and accounts for about half of the cases of primary amenorrhea.
Defects in BMP15 are the cause of premature ovarian failure type 4 (POF4) [MIM:300510]. An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol.

Similarity:
Belongs to the TGF-beta family.

Database links:

Entrez Gene: 9210 Human

Entrez Gene: 12155 Mouse

Entrez Gene: 59302 Rat

Omim: 300247 Human

SwissProt: O95972 Human

SwissProt: Q9Z0L4 Mouse

Unigene: 532692 Human

Unigene: 42160 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application
   

BMP15蛋白是骨形态发生蛋白家族的成员,是转化生长因子β超家族的一部分。转化生长因子β超家族包括大量的生长和分化因子家族。据认为,BMP15可能参与卵母细胞成熟和卵泡发育作为同源二聚体,或通过形成具有相关蛋白的异源二聚体,GDF9。