FITC标记的酪氨酸蛋白激酶A5受体抗体上海沪震实业有限公司

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产品名称: FITC标记的酪氨酸蛋白激酶A5受体抗体
英文名称: Anti-Eph receptor A5/FITC
抗体货号: HZ-6599R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/9/1 13:56:00
详细资料:  实验方法技术资料
浏览人数:15
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-Eph receptor A5/FITC Conjugated antibody 

FITC标记的酪氨酸蛋白激酶A5受体抗体

 

英文名称 Anti-Eph receptor A5/FITC
中文名称 FITC标记的酪氨酸蛋白激酶A5受体抗体
别    名 bsk; CEK 7; Eck like sequence 1; EHK 1; Els 1; Eph homology kinase 1; EphA5; Ephrin type A receptor 5; HEK 7; Receptor protein tyrosine kinase HEK 7; Rek 7; TYRO 4; Tyrosine protein kinase receptor EHK 1; EPHA5_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  发育生物学  神经生物学  信号转导  激酶和***酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Rabbit, Guinea Pig, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 114kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EphA5/Eph receptor A5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
EphA5, also known as Ehk1, Bsk, Cek7, Hek7, and Rek7, is a member of the Eph receptor family, which binds members of the Ephrin ligand family. Two classes of receptors exist, designated A and B, that have an extracellular domain made up of a globular domain, a cysteine-rich domain, and two fibronectin type III domains, followed by the transmembrane region and cytoplasmic region. The cytoplasmic region is a juxtamembrane region with two tyrosines, the major autophosphorylation sites, along with a kinase domain, and a conserved sterile alpha motif (SAM) in the C-terminus, the latter including one conserved tyrosine.

Subunit:
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite.

Tissue Specificity:
Almost exclusively expressed in the nervous system in cortical neurons, cerebellar Purkinje cells and pyramidal neurons within the cortex and hippocampus. Display an increasing gradient of expression from the forebrain to hindbrain and spinal cord.

Similarity:
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
Contains 1 Eph LBD (Eph ligand-binding) domain.
Contains 2 fibronectin type-III domains.
Contains 1 protein kinase domain.
Contains 1 SAM (sterile alpha motif) domain.

Database links:

Entrez Gene: 2044 Human

Entrez Gene: 13839 Mouse

Entrez Gene: 79208 Rat

Omim: 600004 Human

SwissProt: P54755 Chicken

SwissProt: P54756 Human

SwissProt: Q60629 Mouse

SwissProt: P54757 Rat

Unigene: 654492 Human

Unigene: 137991 Mouse

Unigene: 438006 Mouse

Unigene: 24569 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

EPHA5,也称为EHK1、BSK、CEK7、HEK7和Rek7,是EFP-受体家族的成员,它与EPHRIN配体家族的成员结合。存在两类受体,A和B,其胞外域由球状结构域、富含半胱氨酸的结构域和两种纤连蛋白III型结构域组成,其次是跨膜区和胞质区。胞质区是具有两个酪氨酸的主要膜区,主要的***酸化位点,以及激酶结构域,以及C-末端中的保守的无菌α基序(山姆),后者包括一个保守的酪氨酸。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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