FITC标记的17-β-羟脱氢酶6抗体上海沪震实业有限公司

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产品名称: FITC标记的17-β-羟脱氢酶6抗体
英文名称: Anti-HSD17B6/FITC
抗体货号: HZ-6592R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: Flow-Cyt=1:50-200 IF=1:50-200
更新时间: 2018/9/12 11:24:00
详细资料:  实验方法技术资料
浏览人数:25
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
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上海·中国-上海
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产品详细描述

 Rabbit Anti-HSD17B6/FITC Conjugated antibody

FITC标记的17-β-羟脱氢酶6抗体

 

英文名称 Anti-HSD17B6/FITC
中文名称 FITC标记的17-β-羟脱氢酶6抗体
别    名 17-beta-HSD 6; 17-beta-HSD6; 17-beta-hydroxysteroid dehydrogenase type 6; 3 hydroxysteroid epimerase; 3(alpha >beta) hydroxysteroid epimerase; 3(alpha >beta) hydroxysteroid epimerasel; 3-alpha->beta-HSE; 3-alpha->beta-hydroxysteroid epimerase; H17B6_HUMAN; HSD17B6; HSE; Hydroxysteroid (17 beta) dehydrogenase 6; Hydroxysteroid (17 beta) dehydrogenase 6 homolog (mouse); Hydroxysteroid 17 beta dehydrogenase 6; NAD+ dependent 3 alpha hydroxysteroid dehydrogenase 3 hydroxysteroid epimerase; NAD+ dependent 3 alpha hydroxysteroid dehydrogenase; Oxidative 3 alpha hydroxysteroid dehydrogenase; Oxidative 3-alpha hydroxysteroid dehydrogenase; Oxidoreductase; Retinol dehydrogenase; RODH; SDR9C6;Short chain dehydrogenase/reductase family 9C, member 6.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 信号转导  生长因子和***  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Horse, 
产品应用 Flow-Cyt=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSD17B6 (70-115aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-***an-3-alpha,17-beta-diol to ***erone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards ***erone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert ***erone to epi-***erone. Androsterone is first oxidized to 5-alpha-***ane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
Tissue specificity; Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.
Sequence similarities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Subcellular Location:
Microsome membrane; Peripheral membrane protein; Lumenal side. Early endosome membrane; Peripheral membrane protein; Lumenal side (Potential).

Tissue Specificity:
Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links:

Entrez Gene: 8630 Human

Entrez Gene: 27400 Mouse

Entrez Gene: 286964 Rat

Omim: 606623 Human

SwissProt: Q3T001 Cow

SwissProt: O14756 Human

SwissProt: Q9R092 Mouse

SwissProt: O54753 Rat

Unigene: 524513 Human

Unigene: 26719 Mouse

Unigene: 10857 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

NAD依赖的氧化还原酶具有广泛的底物特异性,显示出氧化和还原活性(体外)。有17β-羟类固醇脱氢酶活性对各种类固醇(体外)。将5-α-雄甾-3-α,17β-二醇转化为雄***和雌二醇至雌***(体外)。对雄***具有体外α-羟类固醇脱氢酶活性(体外)。对全反式视黄醇具有视黄醇脱氢酶活性(体外)。可将雄***转化为表雄***。首先将Androsterone氧化为5-α-雄甾-3,17-二***,然后还原成表雄***。可以作用于C-19和C-21 -3α-羟基甾体。

组织特异性:在肝和前列腺中检测到(蛋白水平)。在***肝脏、肺、脑、胎盘、前列腺、肾上腺、睾丸、乳腺、脾脏、脊髓和子宫中检测到。在尾状核、杏仁核、胼胝体、海马、黑质、丘脑等较低水平。检测胎儿肺、肝、脑。

 

序列相似性,属于短链脱氢酶/还原酶(SDR)家族。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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