FITC标记的亲脂性蛋白B抗体
产品名称： FITC标记的亲脂性蛋白B抗体
英文名称： Anti-Lipophilin B/FITC
产品编号： HZ-6546R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-Lipophilin B/FITC Conjugated antibody
FITC标记的亲脂性蛋白B抗体
| 英文名称 | Anti-Lipophilin B/FITC |
| 中文名称 | FITC标记的亲脂性蛋白B抗体 |
| 别 名 | LIPB; LIPHB; Lipophilin B (uteroglobin family member) prostatein like; LipophilinB; LPHB; Prostatein like lipophilin B; SCGB1D2; Secretoglobin family 1D member 2; SG1D2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 信号转导 生长因子和激素 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 8kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Lipophilin B (61-90aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. Function: May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones. Subcellular Location: Secreted Tissue Specificity: ighest expression was found in skeletal muscle. Expressed as well in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. Database links: UniProtKB/Swiss-Prot: O95969.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质是脂蛋白亚家族的成员，是子宫内膜超家族的一部分，是前列腺大鼠腹侧前列腺的主要分泌糖蛋白的原噬菌体的同源物。脂蛋白基因产物广泛表达于正常组织，尤其在内分泌反应器官中。假设人亲脂性素是前列腺素的功能对应物，它们可以通过类固醇激素转录调节，具有结合雄激素、其他类固醇和可能结合和浓缩雌甾霉素的能力，这是一种广泛用于前列腺癌的化疗剂。虽然该基因已被报道在10号染色体上，但该序列似乎来自11号染色体上的一组基因，其中包括乳房珠蛋白2。